Fakih R - Search Results

1

Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons.

Song P, Peng W, Sauve V, Fakih R, Xie Z, Ysselstein D, Krainc T, Wong YC, Mencacci NE, Savas JN, Surmeier DJ, Gehring K, Krainc D. Song P, et al. Among authors: fakih r. Neuron. 2023 Dec 6;111(23):3775-3788.e7. doi: 10.1016/j.neuron.2023.08.018. Epub 2023 Sep 15. Neuron. 2023. PMID: 37716354

2

Structural basis for feedforward control in the PINK1/Parkin pathway.

Sauvé V, Sung G, MacDougall EJ, Kozlov G, Saran A, Fakih R, Fon EA, Gehring K. Sauvé V, et al. Among authors: fakih r. EMBO J. 2022 Jun 14;41(12):e109460. doi: 10.15252/embj.2021109460. Epub 2022 May 2. EMBO J. 2022. PMID: 35491809 Free PMC article.

3

Structure of the second phosphoubiquitin-binding site in parkin.

Fakih R, Sauvé V, Gehring K. Fakih R, et al. J Biol Chem. 2022 Jul;298(7):102114. doi: 10.1016/j.jbc.2022.102114. Epub 2022 Jun 8. J Biol Chem. 2022. PMID: 35690145 Free PMC article.

4

Feedforward activation of PRKN/parkin.

Fakih R, Sauvé V, Gehring K. Fakih R, et al. Autophagy. 2023 Feb;19(2):729-730. doi: 10.1080/15548627.2022.2100615. Epub 2022 Jul 15. Autophagy. 2023. PMID: 35838500 Free PMC article.

5

The double lives of phosphatases of regenerating liver: A structural view of their catalytic and noncatalytic activities.

Gehring K, Kozlov G, Yang M, Fakih R. Gehring K, et al. Among authors: fakih r. J Biol Chem. 2022 Jan;298(1):101471. doi: 10.1016/j.jbc.2021.101471. Epub 2021 Dec 7. J Biol Chem. 2022. PMID: 34890645 Free PMC article. Review.

6

Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver.

Fakih R, Goldstein RH, Kozlov G, Gehring K. Fakih R, et al. J Biol Chem. 2023 Apr;299(4):103055. doi: 10.1016/j.jbc.2023.103055. Epub 2023 Feb 22. J Biol Chem. 2023. PMID: 36822330 Free PMC article.

7

Mg²⁺-ATP Sensing in CNNM, a Putative Magnesium Transporter.

Chen YS, Kozlov G, Fakih R, Yang M, Zhang Z, Kovrigin EL, Gehring K. Chen YS, et al. Among authors: fakih r. Structure. 2020 Mar 3;28(3):324-335.e4. doi: 10.1016/j.str.2019.11.016. Epub 2019 Dec 18. Structure. 2020. PMID: 31864811 Free article.

8

Crystal structure of an archaeal CorB magnesium transporter.

Chen YS, Kozlov G, Moeller BE, Rohaim A, Fakih R, Roux B, Burke JE, Gehring K. Chen YS, et al. Among authors: fakih r. Nat Commun. 2021 Jun 29;12(1):4028. doi: 10.1038/s41467-021-24282-7. Nat Commun. 2021. PMID: 34188059 Free PMC article.

9

The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg²⁺ efflux activity.

Chen YS, Kozlov G, Fakih R, Funato Y, Miki H, Gehring K. Chen YS, et al. Among authors: fakih r. J Biol Chem. 2018 Dec 28;293(52):19998-20007. doi: 10.1074/jbc.RA118.005672. Epub 2018 Oct 19. J Biol Chem. 2018. PMID: 30341174 Free PMC article.

10

Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.

Yang M, Chen YS, Ichikawa M, Calles-Garcia D, Basu K, Fakih R, Bui KH, Gehring K. Yang M, et al. Among authors: fakih r. J Struct Biol. 2019 Oct 1;208(1):43-50. doi: 10.1016/j.jsb.2019.07.009. Epub 2019 Jul 22. J Struct Biol. 2019. PMID: 31344437

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