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Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation.
Salvato I, Ricciardi L, Dal Col J, Nigro A, Giurato G, Memoli D, Sellitto A, Lamparelli EP, Crescenzi MA, Vitale M, Vatrella A, Nucera F, Brun P, Caicci F, Dama P, Stiff T, Castellano L, Idrees S, Johansen MD, Faiz A, Wark PA, Hansbro PM, Adcock IM, Caramori G, Stellato C. Salvato I, et al. Among authors: faiz a. Front Immunol. 2023 Jul 7;14:1192028. doi: 10.3389/fimmu.2023.1192028. eCollection 2023. Front Immunol. 2023. PMID: 37483631 Free PMC article.
Animal and translational models of SARS-CoV-2 infection and COVID-19.
Johansen MD, Irving A, Montagutelli X, Tate MD, Rudloff I, Nold MF, Hansbro NG, Kim RY, Donovan C, Liu G, Faiz A, Short KR, Lyons JG, McCaughan GW, Gorrell MD, Cole A, Moreno C, Couteur D, Hesselson D, Triccas J, Neely GG, Gamble JR, Simpson SJ, Saunders BM, Oliver BG, Britton WJ, Wark PA, Nold-Petry CA, Hansbro PM. Johansen MD, et al. Among authors: faiz a. Mucosal Immunol. 2020 Nov;13(6):877-891. doi: 10.1038/s41385-020-00340-z. Epub 2020 Aug 20. Mucosal Immunol. 2020. PMID: 32820248 Free PMC article. Review.
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing.
Johansen MD, Mahbub RM, Idrees S, Nguyen DH, Miemczyk S, Pathinayake P, Nichol K, Hansbro NG, Gearing LJ, Hertzog PJ, Gallego-Ortega D, Britton WJ, Saunders BM, Wark PA, Faiz A, Hansbro PM. Johansen MD, et al. Among authors: faiz a. Am J Respir Crit Care Med. 2022 Sep 15;206(6):712-729. doi: 10.1164/rccm.202108-1901OC. Am J Respir Crit Care Med. 2022. PMID: 35549656 Free PMC article.
Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap.
Tu X, Kim RY, Brown AC, de Jong E, Jones-Freeman B, Ali MK, Gomez HM, Budden KF, Starkey MR, Cameron GJM, Loering S, Nguyen DH, Nair PM, Haw TJ, Alemao CA, Faiz A, Tay HL, Wark PAB, Knight DA, Foster PS, Bosco A, Horvat JC, Hansbro PM, Donovan C. Tu X, et al. Among authors: faiz a. J Allergy Clin Immunol. 2022 Oct;150(4):817-829.e6. doi: 10.1016/j.jaci.2022.04.032. Epub 2022 May 25. J Allergy Clin Immunol. 2022. PMID: 35643377
Smoking induces shifts in cellular composition and transcriptome within the bronchial mucus barrier.
Rathnayake SNH, Ditz B, van Nijnatten J, Sadaf T, Hansbro PM, Brandsma CA, Timens W, van Schadewijk A, Hiemstra PS, Ten Hacken NHT, Oliver B, Kerstjens HAM, van den Berge M, Faiz A. Rathnayake SNH, et al. Among authors: faiz a. Respirology. 2023 Feb;28(2):132-142. doi: 10.1111/resp.14401. Epub 2022 Nov 22. Respirology. 2023. PMID: 36414410 Free PMC article.
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.
Van Eeckhoutte HP, Donovan C, Kim RY, Conlon TM, Ansari M, Khan H, Jayaraman R, Hansbro NG, Dondelinger Y, Delanghe T, Beal AM, Geddes B, Bertin J, Vanden Berghe T, De Volder J, Maes T, Vandenabeele P, Vanaudenaerde BM, Deforce D, Škevin S, Van Nieuwerburgh F, Verhamme FM, Joos GF, Idrees S, Schiller HB, Yildirim AÖ, Faiz A, Bertrand MJM, Brusselle GG, Hansbro PM, Bracke KR. Van Eeckhoutte HP, et al. Among authors: faiz a. Eur Respir J. 2023 Apr 1;61(4):2201506. doi: 10.1183/13993003.01506-2022. Print 2023 Apr. Eur Respir J. 2023. PMID: 36549711
IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels.
Faiz A, Mahbub RM, Boedijono FS, Tomassen MI, Kooistra W, Timens W, Nawijn M, Hansbro PM, Johansen MD, Pouwels SD, Heijink IH, Massip F, de Biase MS, Schwarz RF, Adcock IM, Chung KF, van der Does A, Hiemstra PS, Goulaouic H, Xing H, Abdulai R, de Rinaldis E, Cunoosamy D, Harel S, Lederer D, Nivens MC, Wark PA, Kerstjens HAM, Hylkema MN, Brandsma CA, van den Berge M. Faiz A, et al. Am J Respir Crit Care Med. 2023 Nov 15;208(10):1075-1087. doi: 10.1164/rccm.202210-1881OC. Am J Respir Crit Care Med. 2023. PMID: 37708400 Free PMC article.
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.
Liu G, Haw TJ, Starkey MR, Philp AM, Pavlidis S, Nalkurthi C, Nair PM, Gomez HM, Hanish I, Hsu AC, Hortle E, Pickles S, Rojas-Quintero J, Estepar RSJ, Marshall JE, Kim RY, Collison AM, Mattes J, Idrees S, Faiz A, Hansbro NG, Fukui R, Murakami Y, Cheng HS, Tan NS, Chotirmall SH, Horvat JC, Foster PS, Oliver BG, Polverino F, Ieni A, Monaco F, Caramori G, Sohal SS, Bracke KR, Wark PA, Adcock IM, Miyake K, Sin DD, Hansbro PM. Liu G, et al. Among authors: faiz a. Nat Commun. 2023 Nov 14;14(1):7349. doi: 10.1038/s41467-023-42913-z. Nat Commun. 2023. PMID: 37963864 Free PMC article.
206 results