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Update 1 of: Beta-strand mimetics.
Loughlin WA, Tyndall JD, Glenn MP, Hill TA, Fairlie DP. Loughlin WA, et al. Among authors: fairlie dp. Chem Rev. 2010 Jun 9;110(6):PR32-69. doi: 10.1021/cr900395y. Epub 2010 Apr 12. Chem Rev. 2010. PMID: 20384343 Review. No abstract available.
Comparative α-helicity of cyclic pentapeptides in water.
de Araujo AD, Hoang HN, Kok WM, Diness F, Gupta P, Hill TA, Driver RW, Price DA, Liras S, Fairlie DP. de Araujo AD, et al. Among authors: fairlie dp. Angew Chem Int Ed Engl. 2014 Jul 1;53(27):6965-9. doi: 10.1002/anie.201310245. Epub 2014 May 14. Angew Chem Int Ed Engl. 2014. PMID: 24828311
Improving on nature: making a cyclic heptapeptide orally bioavailable.
Nielsen DS, Hoang HN, Lohman RJ, Hill TA, Lucke AJ, Craik DJ, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Fairlie DP. Nielsen DS, et al. Among authors: fairlie dp. Angew Chem Int Ed Engl. 2014 Nov 3;53(45):12059-63. doi: 10.1002/anie.201405364. Epub 2014 Sep 12. Angew Chem Int Ed Engl. 2014. PMID: 25219505
Constraining cyclic peptides to mimic protein structure motifs.
Hill TA, Shepherd NE, Diness F, Fairlie DP. Hill TA, et al. Among authors: fairlie dp. Angew Chem Int Ed Engl. 2014 Nov 24;53(48):13020-41. doi: 10.1002/anie.201401058. Epub 2014 Oct 6. Angew Chem Int Ed Engl. 2014. PMID: 25287434 Review.
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.
Hill TA, Lohman RJ, Hoang HN, Nielsen DS, Scully CC, Kok WM, Liu L, Lucke AJ, Stoermer MJ, Schroeder CI, Chaousis S, Colless B, Bernhardt PV, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Craik DJ, Fairlie DP. Hill TA, et al. Among authors: fairlie dp. ACS Med Chem Lett. 2014 Aug 4;5(10):1148-51. doi: 10.1021/ml5002823. eCollection 2014 Oct 9. ACS Med Chem Lett. 2014. PMID: 25313329 Free PMC article.
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.
Hoang HN, Song K, Hill TA, Derksen DR, Edmonds DJ, Kok WM, Limberakis C, Liras S, Loria PM, Mascitti V, Mathiowetz AM, Mitchell JM, Piotrowski DW, Price DA, Stanton RV, Suen JY, Withka JM, Griffith DA, Fairlie DP. Hoang HN, et al. Among authors: fairlie dp. J Med Chem. 2015 May 14;58(9):4080-5. doi: 10.1021/acs.jmedchem.5b00166. Epub 2015 Apr 16. J Med Chem. 2015. PMID: 25839426
390 results