Fairlie DP - Search Results

1

Structure, function and pathophysiology of protease activated receptors.

Adams MN, Ramachandran R, Yau MK, Suen JY, Fairlie DP, Hollenberg MD, Hooper JD. Adams MN, et al. Among authors: fairlie dp. Pharmacol Ther. 2011 Jun;130(3):248-82. doi: 10.1016/j.pharmthera.2011.01.003. Epub 2011 Jan 26. Pharmacol Ther. 2011. PMID: 21277892 Review.

2

Protease-activated receptor-2 peptides activate neurokinin-1 receptors in the mouse isolated trachea.

Abey HT, Fairlie DP, Moffatt JD, Balzary RW, Cocks TM. Abey HT, et al. Among authors: fairlie dp. J Pharmacol Exp Ther. 2006 May;317(2):598-605. doi: 10.1124/jpet.105.097121. Epub 2006 Jan 24. J Pharmacol Exp Ther. 2006. PMID: 16434565

3

Agonists and antagonists of protease activated receptors (PARs).

Barry GD, Le GT, Fairlie DP. Barry GD, et al. Among authors: fairlie dp. Curr Med Chem. 2006;13(3):243-65. doi: 10.2174/092986706775476070. Curr Med Chem. 2006. PMID: 16475935 Review.

4

A refined agonist pharmacophore for protease activated receptor 2.

Barry GD, Suen JY, Low HB, Pfeiffer B, Flanagan B, Halili M, Le GT, Fairlie DP. Barry GD, et al. Among authors: fairlie dp. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5552-7. doi: 10.1016/j.bmcl.2007.08.026. Epub 2007 Aug 16. Bioorg Med Chem Lett. 2007. PMID: 17765542

5

Novel agonists and antagonists for human protease activated receptor 2.

Barry GD, Suen JY, Le GT, Cotterell A, Reid RC, Fairlie DP. Barry GD, et al. Among authors: fairlie dp. J Med Chem. 2010 Oct 28;53(20):7428-40. doi: 10.1021/jm100984y. J Med Chem. 2010. PMID: 20873792

6

Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells.

Suen JY, Gardiner B, Grimmond S, Fairlie DP. Suen JY, et al. Among authors: fairlie dp. PLoS One. 2010 Nov 2;5(11):e13809. doi: 10.1371/journal.pone.0013809. PLoS One. 2010. PMID: 21072196 Free PMC article.

7

Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110).

Suen JY, Barry GD, Lohman RJ, Halili MA, Cotterell AJ, Le GT, Fairlie DP. Suen JY, et al. Among authors: fairlie dp. Br J Pharmacol. 2012 Mar;165(5):1413-23. doi: 10.1111/j.1476-5381.2011.01610.x. Br J Pharmacol. 2012. PMID: 21806599 Free PMC article.

8

Antagonism of protease-activated receptor 2 protects against experimental colitis.

Lohman RJ, Cotterell AJ, Suen J, Liu L, Do AT, Vesey DA, Fairlie DP. Lohman RJ, et al. Among authors: fairlie dp. J Pharmacol Exp Ther. 2012 Feb;340(2):256-65. doi: 10.1124/jpet.111.187062. Epub 2011 Oct 25. J Pharmacol Exp Ther. 2012. PMID: 22028393

9

An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats.

Lohman RJ, Cotterell AJ, Barry GD, Liu L, Suen JY, Vesey DA, Fairlie DP. Lohman RJ, et al. Among authors: fairlie dp. FASEB J. 2012 Jul;26(7):2877-87. doi: 10.1096/fj.11-201004. Epub 2012 Mar 30. FASEB J. 2012. PMID: 22467762

10

An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats.

Iyer A, Lim J, Poudyal H, Reid RC, Suen JY, Webster J, Prins JB, Whitehead JP, Fairlie DP, Brown L. Iyer A, et al. Among authors: fairlie dp. Diabetes. 2012 Sep;61(9):2320-9. doi: 10.2337/db11-1179. Diabetes. 2012. PMID: 22923652 Free PMC article.

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