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Systemic IFN-alpha drives kidney nephritis in B6.Sle123 mice.
Fairhurst AM, Mathian A, Connolly JE, Wang A, Gray HF, George TA, Boudreaux CD, Zhou XJ, Li QZ, Koutouzov S, Banchereau J, Wakeland EK. Fairhurst AM, et al. Eur J Immunol. 2008 Jul;38(7):1948-60. doi: 10.1002/eji.200837925. Eur J Immunol. 2008. PMID: 18506882 Free PMC article.
B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice.
Hwang SH, Lee H, Yamamoto M, Jones LA, Dayalan J, Hopkins R, Zhou XJ, Yarovinsky F, Connolly JE, Curotto de Lafaille MA, Wakeland EK, Fairhurst AM. Hwang SH, et al. Among authors: fairhurst am. J Immunol. 2012 Dec 15;189(12):5786-96. doi: 10.4049/jimmunol.1202195. Epub 2012 Nov 12. J Immunol. 2012. PMID: 23150717 Free PMC article.
Enhanced neutralizing antibody titers and Th1 polarization from a novel Escherichia coli derived pandemic influenza vaccine.
Skibinski DA, Hanson BJ, Lin Y, von Messling V, Jegerlehner A, Tee JB, Chye de H, Wong SK, Ng AA, Lee HY, Au B, Lee BT, Santoso L, Poidinger M, Fairhurst AM, Matter A, Bachmann MF, Saudan P, Connolly JE. Skibinski DA, et al. Among authors: fairhurst am. PLoS One. 2013 Oct 18;8(10):e76571. doi: 10.1371/journal.pone.0076571. eCollection 2013. PLoS One. 2013. PMID: 24204639 Free PMC article.
RNA sensing by conventional dendritic cells is central to the development of lupus nephritis.
Celhar T, Hopkins R, Thornhill SI, De Magalhaes R, Hwang SH, Lee HY, Yasuga H, Jones LA, Casco J, Lee B, Thamboo TP, Zhou XJ, Poidinger M, Connolly JE, Wakeland EK, Fairhurst AM. Celhar T, et al. Among authors: fairhurst am. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6195-204. doi: 10.1073/pnas.1507052112. Epub 2015 Oct 28. Proc Natl Acad Sci U S A. 2015. PMID: 26512111 Free PMC article.
TLR7 and TLR9 ligands regulate antigen presentation by macrophages.
Celhar T, Pereira-Lopes S, Thornhill SI, Lee HY, Dhillon MK, Poidinger M, Connolly JE, Lim LH, Biswas SK, Fairhurst AM. Celhar T, et al. Among authors: fairhurst am. Int Immunol. 2016 May;28(5):223-32. doi: 10.1093/intimm/dxv066. Epub 2015 Nov 13. Int Immunol. 2016. PMID: 26567289 Free PMC article.
52 results