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Synthesis and biological evaluation of novel N3-substituted dihydropyrimidine derivatives as T-type calcium channel blockers and their efficacy as analgesics in mouse models of inflammatory pain.
Teleb M, Zhang FX, Huang J, Gadotti VM, Farghaly AM, AboulWafa OM, Zamponi GW, Fahmy H. Teleb M, et al. Among authors: fahmy h. Bioorg Med Chem. 2017 Mar 15;25(6):1926-1938. doi: 10.1016/j.bmc.2017.02.015. Epub 2017 Feb 13. Bioorg Med Chem. 2017. PMID: 28233679
Design, synthesis, structural optimization, SAR, in silico prediction of physicochemical properties and pharmacological evaluation of novel & potent thiazolo[4,5-d]pyrimidine corticotropin releasing factor (CRF) receptor antagonists.
Islam MR, Teleb M, Karageorgos V, Sakellaris S, Papadopoulos M, Pirmettis I, Fronczek FR, Liapakis G, Fahmy H. Islam MR, et al. Among authors: fahmy h. Eur J Pharm Sci. 2022 Feb 1;169:106084. doi: 10.1016/j.ejps.2021.106084. Epub 2021 Nov 29. Eur J Pharm Sci. 2022. PMID: 34856350 Free article.
A semi-synthetic analog of the cembranoid sarcophine.
Fahmy H, Zjawiony JK, Khalifa S, Fronczek FR. Fahmy H, et al. Acta Crystallogr C. 2003 Feb;59(Pt 2):o85-7. doi: 10.1107/s0108270103001288. Epub 2003 Jan 31. Acta Crystallogr C. 2003. PMID: 12574663
208 results