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Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia.
Scott-Hewitt N, Perrucci F, Morini R, Erreni M, Mahoney M, Witkowska A, Carey A, Faggiani E, Schuetz LT, Mason S, Tamborini M, Bizzotto M, Passoni L, Filipello F, Jahn R, Stevens B, Matteoli M. Scott-Hewitt N, et al. Among authors: faggiani e. EMBO J. 2020 Aug 17;39(16):e105380. doi: 10.15252/embj.2020105380. Epub 2020 Jul 13. EMBO J. 2020. PMID: 32657463 Free PMC article.
Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development.
Tagliatti E, Desiato G, Mancinelli S, Bizzotto M, Gagliani MC, Faggiani E, Hernández-Soto R, Cugurra A, Poliseno P, Miotto M, Argüello RJ, Filipello F, Cortese K, Morini R, Lodato S, Matteoli M. Tagliatti E, et al. Among authors: faggiani e. Immunity. 2024 Jan 9;57(1):86-105.e9. doi: 10.1016/j.immuni.2023.12.002. Epub 2023 Dec 29. Immunity. 2024. PMID: 38159572 Free PMC article.
Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons.
De Giorgi F, Laferrière F, Zinghirino F, Faggiani E, Lends A, Bertoni M, Yu X, Grélard A, Morvan E, Habenstein B, Dutheil N, Doudnikoff E, Daniel J, Claverol S, Qin C, Loquet A, Bezard E, Ichas F. De Giorgi F, et al. Among authors: faggiani e. Sci Adv. 2020 Oct 2;6(40):eabc4364. doi: 10.1126/sciadv.abc4364. Print 2020 Oct. Sci Adv. 2020. PMID: 33008896 Free PMC article.
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.
Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, Cragg S, Dehay B, Bitan G, Matute C, Bezard E, Wade-Martins R. Bengoa-Vergniory N, et al. Among authors: faggiani e. Nat Commun. 2020 Sep 28;11(1):4885. doi: 10.1038/s41467-020-18689-x. Nat Commun. 2020. PMID: 32985503 Free PMC article.
16 results