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Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.
Shah SM, Demidova EV, Ringenbach S, Faezov B, Andrake M, Gandhi A, Mur P, Viana-Errasti J, Xiu J, Swensen J, Valle L, Dunbrack RL Jr, Hall MJ, Arora S. Shah SM, et al. Among authors: faezov b. Cancer Res Commun. 2024 Jan 26;4(1):213-225. doi: 10.1158/2767-9764.CRC-23-0312. Epub 2024 Jan 8. Cancer Res Commun. 2024. PMID: 38282550 Free PMC article.
FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55⍺/PP2A phosphatase.
Wasserman JS, Faezov B, Patel KR, Kurimchak AN, Palacio SM, Fowle H, McEwan BC, Xu Q, Zhao Z, Cressey L, Johnson N, Duncan JS, Kettenbach AN, Dunbrack RL, Graña X. Wasserman JS, et al. Among authors: faezov b. bioRxiv [Preprint]. 2023 Mar 17:2023.03.06.531310. doi: 10.1101/2023.03.06.531310. bioRxiv. 2023. PMID: 36945596 Free PMC article. Preprint.
Development and Utility of a PAK1-Selective Degrader.
Chow HY, Karchugina S, Groendyke BJ, Toenjes S, Hatcher J, Donovan KA, Fischer ES, Abalakov G, Faezov B, Dunbrack R, Gray NS, Chernoff J. Chow HY, et al. Among authors: faezov b. J Med Chem. 2022 Dec 8;65(23):15627-15641. doi: 10.1021/acs.jmedchem.2c00756. Epub 2022 Nov 23. J Med Chem. 2022. PMID: 36416208 Free PMC article.
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC).
Makhov P, Bychkov I, Faezov B, Deneka A, Kudinov A, Nicolas E, Brebion R, Avril E, Cai KQ, Kharin LV, Voloshin M, Frantsiyants E, Karnaukhov N, Kit OI, Topchu I, Fazliyeva R, Nikonova AS, Serebriiskii IG, Borghaei H, Edelman M, Dulaimi E, Golemis EA, Boumber Y. Makhov P, et al. Among authors: faezov b. Oncogenesis. 2021 Mar 15;10(3):29. doi: 10.1038/s41389-021-00317-y. Oncogenesis. 2021. PMID: 33723247 Free PMC article.