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Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations.
Mol Ther Nucleic Acids. 2021 Aug 19;25:585-602. doi: 10.1016/j.omtn.2021.08.003. eCollection 2021 Sep 3.
Mol Ther Nucleic Acids. 2021.
PMID: 34589280
Free PMC article.
Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility.
Styr B, Gonen N, Zarhin D, Ruggiero A, Atsmon R, Gazit N, Braun G, Frere S, Vertkin I, Shapira I, Harel M, Heim LR, Katsenelson M, Rechnitz O, Fadila S, Derdikman D, Rubinstein M, Geiger T, Ruppin E, Slutsky I.
Styr B, et al. Among authors: fadila s.
Neuron. 2019 Jun 5;102(5):1009-1024.e8. doi: 10.1016/j.neuron.2019.03.045. Epub 2019 Apr 29.
Neuron. 2019.
PMID: 31047779
Free PMC article.
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Convulsive seizures and some behavioral comorbidities are uncoupled in the Scn1aA1783V Dravet syndrome mouse model.
Fadila S, Quinn S, Turchetti Maia A, Yakubovich D, Ovadia M, Anderson KL, Giladi M, Rubinstein M.
Fadila S, et al.
Epilepsia. 2020 Oct;61(10):2289-2300. doi: 10.1111/epi.16662. Epub 2020 Aug 31.
Epilepsia. 2020.
PMID: 32865826
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Developmental alterations in firing properties of hippocampal CA1 inhibitory and excitatory neurons in a mouse model of Dravet syndrome.
Almog Y, Fadila S, Brusel M, Mavashov A, Anderson K, Rubinstein M.
Almog Y, et al. Among authors: fadila s.
Neurobiol Dis. 2021 Jan;148:105209. doi: 10.1016/j.nbd.2020.105209. Epub 2020 Nov 30.
Neurobiol Dis. 2021.
PMID: 33271326
Free article.
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Viral vector-mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome.
Fadila S, Beucher B, Dopeso-Reyes IG, Mavashov A, Brusel M, Anderson K, Ismeurt C, Goldberg EM, Ricobaraza A, Hernandez-Alcoceba R, Kremer EJ, Rubinstein M.
Fadila S, et al.
J Clin Invest. 2023 Jun 15;133(12):e159316. doi: 10.1172/JCI159316.
J Clin Invest. 2023.
PMID: 37192002
Free PMC article.
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Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome.
Ricobaraza A, Bunuales M, Gonzalez-Aparicio M, Fadila S, Rubinstein M, Vides-Urrestarazu I, Banderas J, Sola-Sevilla N, Sanchez-Carpintero R, Lanciego JL, Roda E, Honrubia A, Arnaiz P, Hernandez-Alcoceba R.
Ricobaraza A, et al. Among authors: fadila s.
J Mol Med (Berl). 2023 Dec;101(12):1587-1601. doi: 10.1007/s00109-023-02383-8. Epub 2023 Oct 11.
J Mol Med (Berl). 2023.
PMID: 37819378
Free PMC article.
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