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Human chemically-derived hepatic progenitors (hCdHs) as a source of liver organoid generation: Application in regenerative medicine, disease modeling, and toxicology testing.
Salas-Silva S, Kim Y, Kim TH, Kim M, Seo D, Choi J, Factor VM, Seo HR, Song Y, Choi GS, Jung YK, Kim K, Lee KG, Jeong J, Shin JH, Choi D. Salas-Silva S, et al. Among authors: factor vm. Biomaterials. 2023 Dec;303:122360. doi: 10.1016/j.biomaterials.2023.122360. Epub 2023 Oct 20. Biomaterials. 2023. PMID: 38465578 Free article.
Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex.
Sun Y, Baechler SA, Zhang X, Kumar S, Factor VM, Arakawa Y, Chau CH, Okamoto K, Parikh A, Walker B, Su YP, Chen J, Ting T, Huang SN, Beck E, Itkin Z, McKnight C, Xie C, Roper N, Nijhawan D, Figg WD, Meltzer PS, Yang JC, Thomas CJ, Pommier Y. Sun Y, et al. Among authors: factor vm. Nat Commun. 2023 Jun 23;14(1):3762. doi: 10.1038/s41467-023-39374-9. Nat Commun. 2023. PMID: 37353483 Free PMC article.
Transplantation of patient-specific bile duct bioengineered with chemically reprogrammed and microtopographically differentiated cells.
Buisson EM, Park SH, Kim M, Kang K, Yoon S, Lee JE, Kim YW, Lee NK, Jeong MA, Kang BK, Lee SB, Factor VM, Seo D, Kim H, Jeong J, Kim HJ, Choi D. Buisson EM, et al. Among authors: factor vm. Bioeng Transl Med. 2021 Sep 3;7(1):e10252. doi: 10.1002/btm2.10252. eCollection 2022 Jan. Bioeng Transl Med. 2021. PMID: 35079629 Free PMC article.
Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers.
Høgdall D, O'Rourke CJ, Dehlendorff C, Larsen OF, Jensen LH, Johansen AZ, Dang H, Factor VM, Grunnet M, Mau-Sørensen M, Oliveira DVNP, Linnemann D, Boisen MK, Wang XW, Johansen JS, Andersen JB. Høgdall D, et al. Among authors: factor vm. Clin Cancer Res. 2020 Nov 1;26(21):5655-5667. doi: 10.1158/1078-0432.CCR-19-2700. Epub 2020 Sep 15. Clin Cancer Res. 2020. PMID: 32933994 Free PMC article.
c-Met Signaling Is Essential for Mouse Adult Liver Progenitor Cells Expansion After Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition and Regulates Cell Phenotypic Switch.
Almalé L, García-Álvaro M, Martínez-Palacián A, García-Bravo M, Lazcanoiturburu N, Addante A, Roncero C, Sanz J, de la O López M, Bragado P, Mikulits W, Factor VM, Thorgeirsson SS, Casal JI, Segovia JC, Rial E, Fabregat I, Herrera B, Sánchez A. Almalé L, et al. Among authors: factor vm. Stem Cells. 2019 Aug;37(8):1108-1118. doi: 10.1002/stem.3038. Epub 2019 Jun 18. Stem Cells. 2019. PMID: 31108004
The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis.
Baechler SA, Factor VM, Dalla Rosa I, Ravji A, Becker D, Khiati S, Miller Jenkins LM, Lang M, Sourbier C, Michaels SA, Neckers LM, Zhang HL, Spinazzola A, Huang SN, Marquardt JU, Pommier Y. Baechler SA, et al. Among authors: factor vm. Nat Commun. 2019 Jan 8;10(1):83. doi: 10.1038/s41467-018-07922-3. Nat Commun. 2019. PMID: 30622257 Free PMC article.
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