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Expression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surfaces of target cells and thereby enhances resistance to superinfection.
Venzke S, Michel N, Allespach I, Fackler OT, Keppler OT. Venzke S, et al. J Virol. 2006 Nov;80(22):11141-52. doi: 10.1128/JVI.01556-06. Epub 2006 Aug 23. J Virol. 2006. PMID: 16928758 Free PMC article.
Recently, we demonstrated that Nef reduces cell surface levels of the human immunodeficiency virus type 1 (HIV-1) entry coreceptor CCR5 (N. Michel, I. Allespach, S. Venzke, O. T. Fackler, and O. T. Keppler, Curr. Biol. 15:714-723, 2005). ...
Recently, we demonstrated that Nef reduces cell surface levels of the human immunodeficiency virus type 1 (HIV-1) entry coreceptor CCR5 (N. …
168 results