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The interferon landscape along the respiratory tract impacts the severity of COVID-19.
Sposito B, Broggi A, Pandolfi L, Crotta S, Clementi N, Ferrarese R, Sisti S, Criscuolo E, Spreafico R, Long JM, Ambrosi A, Liu E, Frangipane V, Saracino L, Bozzini S, Marongiu L, Facchini FA, Bottazzi A, Fossali T, Colombo R, Clementi M, Tagliabue E, Chou J, Pontiroli AE, Meloni F, Wack A, Mancini N, Zanoni I. Sposito B, et al. Among authors: facchini fa. Cell. 2021 Sep 16;184(19):4953-4968.e16. doi: 10.1016/j.cell.2021.08.016. Epub 2021 Aug 19. Cell. 2021. PMID: 34492226 Free PMC article.
Maturation signatures of conventional dendritic cell subtypes in COVID-19 suggest direct viral sensing.
Marongiu L, Protti G, Facchini FA, Valache M, Mingozzi F, Ranzani V, Putignano AR, Salviati L, Bevilacqua V, Curti S, Crosti M, Sarnicola ML, D'Angiò M, Bettini LR, Biondi A, Nespoli L, Tamini N, Clementi N, Mancini N, Abrignani S, Spreafico R, Granucci F. Marongiu L, et al. Among authors: facchini fa. Eur J Immunol. 2022 Jan;52(1):109-122. doi: 10.1002/eji.202149298. Epub 2021 Oct 1. Eur J Immunol. 2022. PMID: 34333764 Free PMC article.
How dendritic cells sense and respond to viral infections.
Marongiu L, Valache M, Facchini FA, Granucci F. Marongiu L, et al. Among authors: facchini fa. Clin Sci (Lond). 2021 Oct 14;135(19):2217-2242. doi: 10.1042/CS20210577. Clin Sci (Lond). 2021. PMID: 34623425 Review.
Specific immunosuppressive role of nanodrugs targeting calcineurin in innate myeloid cells.
Colombo M, Marongiu L, Mingozzi F, Marzi R, Cigni C, Facchini FA, Rotem R, Valache M, Stucchi G, Rocca G, Gornati L, Rizzuto MA, Salvioni L, Zanoni I, Gori A, Prosperi D, Granucci F. Colombo M, et al. Among authors: facchini fa. iScience. 2022 Aug 30;25(10):105042. doi: 10.1016/j.isci.2022.105042. eCollection 2022 Oct 21. iScience. 2022. PMID: 36124235 Free PMC article.
Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists.
Facchini FA, Zaffaroni L, Minotti A, Rapisarda S, Calabrese V, Forcella M, Fusi P, Airoldi C, Ciaramelli C, Billod JM, Schromm AB, Braun H, Palmer C, Beyaert R, Lapenta F, Jerala R, Pirianov G, Martin-Santamaria S, Peri F. Facchini FA, et al. J Med Chem. 2018 Apr 12;61(7):2895-2909. doi: 10.1021/acs.jmedchem.7b01803. Epub 2018 Mar 12. J Med Chem. 2018. PMID: 29494148 Free article.
18 results