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Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart.
van der Velden J, Asselbergs FW, Bakkers J, Batkai S, Bertrand L, Bezzina CR, Bot I, Brundel BJJM, Carrier L, Chamuleau S, Ciccarelli M, Dawson D, Davidson SM, Dendorfer A, Duncker DJ, Eschenhagen T, Fabritz L, Falcão-Pires I, Ferdinandy P, Giacca M, Girao H, Gollmann-Tepeköylü C, Gyongyosi M, Guzik TJ, Hamdani N, Heymans S, Hilfiker A, Hilfiker-Kleiner D, Hoekstra AG, Hulot JS, Kuster DWD, van Laake LW, Lecour S, Leiner T, Linke WA, Lumens J, Lutgens E, Madonna R, Maegdefessel L, Mayr M, van der Meer P, Passier R, Perbellini F, Perrino C, Pesce M, Priori S, Remme CA, Rosenhahn B, Schotten U, Schulz R, Sipido KR, Sluijter JPG, van Steenbeek F, Steffens S, Terracciano CM, Tocchetti CG, Vlasman P, Yeung KK, Zacchigna S, Zwaagman D, Thum T. van der Velden J, et al. Among authors: fabritz l. Cardiovasc Res. 2022 Dec 9;118(15):3016-3051. doi: 10.1093/cvr/cvab370. Cardiovasc Res. 2022. PMID: 34999816 Free PMC article.
PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.
Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld HH, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA. Kirchhof P, et al. Among authors: fabritz l. Circ Cardiovasc Genet. 2011 Apr;4(2):123-33. doi: 10.1161/CIRCGENETICS.110.958058. Epub 2011 Jan 31. Circ Cardiovasc Genet. 2011. PMID: 21282332
Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset.
Chua W, Easter CL, Guasch E, Sitch A, Casadei B, Crijns HJGM, Haase D, Hatem S, Kääb S, Mont L, Schotten U, Sinner MF, Hemming K, Deeks JJ, Kirchhof P, Fabritz L. Chua W, et al. Among authors: fabritz l. BMC Cardiovasc Disord. 2019 May 21;19(1):120. doi: 10.1186/s12872-019-1105-4. BMC Cardiovasc Disord. 2019. PMID: 31113362 Free PMC article.
ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research.
Odening KE, Gomez AM, Dobrev D, Fabritz L, Heinzel FR, Mangoni ME, Molina CE, Sacconi L, Smith G, Stengl M, Thomas D, Zaza A, Remme CA, Heijman J. Odening KE, et al. Among authors: fabritz l. Europace. 2021 Nov 8;23(11):1795-1814. doi: 10.1093/europace/euab142. Europace. 2021. PMID: 34313298 Review.
Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals.
Ripplinger CM, Glukhov AV, Kay MW, Boukens BJ, Chiamvimonvat N, Delisle BP, Fabritz L, Hund TJ, Knollmann BC, Li N, Murray KT, Poelzing S, Quinn TA, Remme CA, Rentschler SL, Rose RA, Posnack NG. Ripplinger CM, et al. Among authors: fabritz l. Am J Physiol Heart Circ Physiol. 2022 Dec 1;323(6):H1137-H1166. doi: 10.1152/ajpheart.00439.2022. Epub 2022 Oct 21. Am J Physiol Heart Circ Physiol. 2022. PMID: 36269644 Free PMC article. Review.
Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study.
Fabritz L, Chua W, Cardoso VR, Al-Taie C, Borof K, Suling A, Krause L, Kany S, Magnussen C, Wegscheider K, Breithardt G, Crijns HJGM, Camm AJ, Gkoutos G, Ellinor PT, Goette A, Schotten U, Wienhues-Thelen UH, Zeller T, Schnabel RB, Zapf A, Kirchhof P. Fabritz L, et al. Cardiovasc Res. 2024 Apr 13:cvae067. doi: 10.1093/cvr/cvae067. Online ahead of print. Cardiovasc Res. 2024. PMID: 38613511
158 results