Fabre G - Search Results

1

The use of human hepatocytes to investigate drug metabolism and CYP enzyme induction.

Klieber S, Torreilles F, Guillou F, Fabre G. Klieber S, et al. Among authors: fabre g. Methods Mol Biol. 2010;640:295-308. doi: 10.1007/978-1-60761-688-7_16. Methods Mol Biol. 2010. PMID: 20645059

2

Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device.

Vivares A, Salle-Lefort S, Arabeyre-Fabre C, Ngo R, Penarier G, Bremond M, Moliner P, Gallas JF, Fabre G, Klieber S. Vivares A, et al. Among authors: fabre g. Xenobiotica. 2015 Jan;45(1):29-44. doi: 10.3109/00498254.2014.944612. Epub 2014 Jul 28. Xenobiotica. 2015. PMID: 25068923

3

Identification of metabolic pathways and enzyme systems involved in the in vitro human hepatic metabolism of dronedarone, a potent new oral antiarrhythmic drug.

Klieber S, Arabeyre-Fabre C, Moliner P, Marti E, Mandray M, Ngo R, Ollier C, Brun P, Fabre G. Klieber S, et al. Among authors: fabre g. Pharmacol Res Perspect. 2014 Jun;2(3):e00044. doi: 10.1002/prp2.44. Epub 2014 Apr 22. Pharmacol Res Perspect. 2014. PMID: 25505590 Free PMC article.

4

Evaluation of Normalization Methods To Predict CYP3A4 Induction in Six Fully Characterized Cryopreserved Human Hepatocyte Preparations and HepaRG Cells.

Vermet H, Raoust N, Ngo R, Esserméant L, Klieber S, Fabre G, Boulenc X. Vermet H, et al. Among authors: fabre g. Drug Metab Dispos. 2016 Jan;44(1):50-60. doi: 10.1124/dmd.115.065581. Epub 2015 Oct 14. Drug Metab Dispos. 2016. PMID: 26467767

5

Contribution of the N-glucuronidation pathway to the overall in vitro metabolic clearance of midazolam in humans.

Klieber S, Hugla S, Ngo R, Arabeyre-Fabre C, Meunier V, Sadoun F, Fedeli O, Rival M, Bourrie M, Guillou F, Maurel P, Fabre G. Klieber S, et al. Among authors: fabre g. Drug Metab Dispos. 2008 May;36(5):851-62. doi: 10.1124/dmd.107.019539. Epub 2008 Feb 6. Drug Metab Dispos. 2008. PMID: 18256203

6

Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up.

Meunier V, Bourrié M, Julian B, Marti E, Guillou F, Berger Y, Fabre G. Meunier V, et al. Among authors: fabre g. Xenobiotica. 2000 Jun;30(6):589-607. doi: 10.1080/004982500406426. Xenobiotica. 2000. PMID: 10923861

7

Evaluation of human hepatocytes under prolonged culture in a novel medium for the maintenance of hepatic differentiation: results with the model pro-inflammatory cytokine interleukin 6.

Li AP, Yang Q, Vermet H, Raoust N, Klieber S, Fabre G. Li AP, et al. Among authors: fabre g. Drug Metab Lett. 2014;8(1):12-8. doi: 10.2174/187231280801140929155351. Drug Metab Lett. 2014. PMID: 25313020

8

In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum.

Daher W, Pelinski L, Klieber S, Sadoun F, Meunier V, Bourrié M, Biot C, Guillou F, Fabre G, Brocard J, Fraisse L, Maffrand JP, Khalife J, Dive D. Daher W, et al. Among authors: fabre g. Drug Metab Dispos. 2006 Apr;34(4):667-82. doi: 10.1124/dmd.104.003202. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415117

9

Human hepatocyte culture.

Pichard L, Raulet E, Fabre G, Ferrini JB, Ourlin JC, Maurel P. Pichard L, et al. Among authors: fabre g. Methods Mol Biol. 2006;320:283-93. doi: 10.1385/1-59259-998-2:283. Methods Mol Biol. 2006. PMID: 16719400

10

Transcriptome response of enterocytes to dietary lipids: impact on cell architecture, signaling, and metabolism genes.

Béaslas O, Torreilles F, Casellas P, Simon D, Fabre G, Lacasa M, Delers F, Chambaz J, Rousset M, Carrière V. Béaslas O, et al. Among authors: fabre g. Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G942-52. doi: 10.1152/ajpgi.90237.2008. Epub 2008 Aug 28. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18755805 Free article.

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