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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2016 | 1 |
2017 | 1 |
2019 | 1 |
2020 | 2 |
2022 | 1 |
2024 | 1 |
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7 results
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Study of an FBXO7 patient mutation reveals Fbxo7 and PI31 co-regulate proteasomes and mitochondria.
FEBS J. 2024 Mar 11. doi: 10.1111/febs.17114. Online ahead of print.
FEBS J. 2024.
PMID: 38466799
CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia.
Grey W, Rio-Machin A, Casado P, Grönroos E, Ali S, Miettinen JJ, Bewicke-Copley F, Parsons A, Heckman CA, Swanton C, Cutillas PR, Gribben J, Fitzgibbon J, Bonnet D.
Grey W, et al.
Sci Transl Med. 2022 Jun 22;14(650):eabn3248. doi: 10.1126/scitranslmed.abn3248. Epub 2022 Jun 22.
Sci Transl Med. 2022.
PMID: 35731890
Free PMC article.
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Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation.
Debets MF, Tastan OY, Wisnovsky SP, Malaker SA, Angelis N, Moeckl LKR, Choi J, Flynn H, Wagner LJS, Bineva-Todd G, Antonopoulos A, Cioce A, Browne WM, Li Z, Briggs DC, Douglas HL, Hess GT, Agbay AJ, Roustan C, Kjaer S, Haslam SM, Snijders AP, Bassik MC, Moerner WE, Li VSW, Bertozzi CR, Schumann B.
Debets MF, et al.
Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25293-25301. doi: 10.1073/pnas.2007297117. Epub 2020 Sep 28.
Proc Natl Acad Sci U S A. 2020.
PMID: 32989128
Free PMC article.
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Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology.
Moccia M, Frett B, Zhang L, Lakkaniga NR, Briggs DC, Chauhan R, Brescia A, Federico G, Yan W, Santoro M, McDonald NQ, Li HY, Carlomagno F.
Moccia M, et al.
J Med Chem. 2020 May 14;63(9):4506-4516. doi: 10.1021/acs.jmedchem.9b01336. Epub 2020 Apr 28.
J Med Chem. 2020.
PMID: 32298114
Free PMC article.
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RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability.
Diring J, Mouilleron S, McDonald NQ, Treisman R.
Diring J, et al.
Nat Cell Biol. 2019 Jul;21(7):845-855. doi: 10.1038/s41556-019-0337-y. Epub 2019 Jun 17.
Nat Cell Biol. 2019.
PMID: 31209295
Free PMC article.
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Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors.
Plenker D, Riedel M, Brägelmann J, Dammert MA, Chauhan R, Knowles PP, Lorenz C, Keul M, Bührmann M, Pagel O, Tischler V, Scheel AH, Schütte D, Song Y, Stark J, Mrugalla F, Alber Y, Richters A, Engel J, Leenders F, Heuckmann JM, Wolf J, Diebold J, Pall G, Peifer M, Aerts M, Gevaert K, Zahedi RP, Buettner R, Shokat KM, McDonald NQ, Kast SM, Gautschi O, Thomas RK, Sos ML.
Plenker D, et al.
Sci Transl Med. 2017 Jun 14;9(394):eaah6144. doi: 10.1126/scitranslmed.aah6144.
Sci Transl Med. 2017.
PMID: 28615362
Free PMC article.
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RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.
Plaza-Menacho I, Barnouin K, Barry R, Borg A, Orme M, Chauhan R, Mouilleron S, Martínez-Torres RJ, Meier P, McDonald NQ.
Plaza-Menacho I, et al.
Cell Rep. 2016 Dec 20;17(12):3319-3332. doi: 10.1016/j.celrep.2016.11.061.
Cell Rep. 2016.
PMID: 28009299
Free PMC article.
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