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A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature.
Am J Respir Crit Care Med. 2021 Dec 15;204(12):1433-1451. doi: 10.1164/rccm.202108-1863OC.
Am J Respir Crit Care Med. 2021.
PMID: 34550870
Free PMC article.
Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension.
Hudalla H, Michael Z, Christodoulou N, Willis GR, Fernandez-Gonzalez A, Filatava EJ, Dieffenbach P, Fredenburgh LE, Stearman RS, Geraci MW, Kourembanas S, Christou H.
Hudalla H, et al.
Am J Respir Cell Mol Biol. 2019 Oct;61(4):512-524. doi: 10.1165/rcmb.2018-0232OC.
Am J Respir Cell Mol Biol. 2019.
PMID: 30951642
Free PMC article.
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NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.
Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA.
Samokhin AO, et al.
Sci Transl Med. 2018 Jun 13;10(445):eaap7294. doi: 10.1126/scitranslmed.aap7294.
Sci Transl Med. 2018.
PMID: 29899023
Free PMC article.
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Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2.
Dieffenbach PB, Haeger CM, Coronata AMF, Choi KM, Varelas X, Tschumperlin DJ, Fredenburgh LE.
Dieffenbach PB, et al.
Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L628-L647. doi: 10.1152/ajplung.00173.2017. Epub 2017 Jun 22.
Am J Physiol Lung Cell Mol Physiol. 2017.
PMID: 28642262
Free PMC article.
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Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension.
Liu F, Haeger CM, Dieffenbach PB, Sicard D, Chrobak I, Coronata AM, Suárez Velandia MM, Vitali S, Colas RA, Norris PC, Marinković A, Liu X, Ma J, Rose CD, Lee SJ, Comhair SA, Erzurum SC, McDonald JD, Serhan CN, Walsh SR, Tschumperlin DJ, Fredenburgh LE.
Liu F, et al.
JCI Insight. 2016 Jun 2;1(8):e86987. doi: 10.1172/jci.insight.86987.
JCI Insight. 2016.
PMID: 27347562
Free PMC article.
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