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The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells.
Cell Rep. 2023 Mar 28;42(3):112245. doi: 10.1016/j.celrep.2023.112245. Epub 2023 Mar 13.
Cell Rep. 2023.
PMID: 36917610
Free PMC article.
CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Liang X, Qiu X, Dionne G, Cunningham CL, Pucak ML, Peng G, Kim YH, Lauer A, Shapiro L, Müller U.
Liang X, et al.
Neuron. 2021 Jul 7;109(13):2131-2149.e15. doi: 10.1016/j.neuron.2021.05.007. Epub 2021 Jun 5.
Neuron. 2021.
PMID: 34089643
Free PMC article.
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TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells.
Cunningham CL, Qiu X, Wu Z, Zhao B, Peng G, Kim YH, Lauer A, Müller U.
Cunningham CL, et al.
Neuron. 2020 Jul 8;107(1):126-143.e8. doi: 10.1016/j.neuron.2020.03.033. Epub 2020 Apr 27.
Neuron. 2020.
PMID: 32343945
Free PMC article.
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Molecular Structure of the Hair Cell Mechanoelectrical Transduction Complex.
Cunningham CL, Müller U.
Cunningham CL, et al.
Cold Spring Harb Perspect Med. 2019 May 1;9(5):a033167. doi: 10.1101/cshperspect.a033167.
Cold Spring Harb Perspect Med. 2019.
PMID: 30082452
Free PMC article.
Review.
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The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.
Cunningham CL, Wu Z, Jafari A, Zhao B, Schrode K, Harkins-Perry S, Lauer A, Müller U.
Cunningham CL, et al.
Elife. 2017 May 15;6:e24318. doi: 10.7554/eLife.24318.
Elife. 2017.
PMID: 28504928
Free PMC article.
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