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Histone Deacetylase Inhibition by Gut Microbe-Generated Short-Chain Fatty Acids Entrains Intestinal Epithelial Circadian Rhythms.
Fawad JA, Luzader DH, Hanson GF, Moutinho TJ Jr, McKinney CA, Mitchell PG, Brown-Steinke K, Kumar A, Park M, Lee S, Bolick DT, Medlock GL, Zhao JY, Rosselot AE, Chou CJ, Eshleman EM, Alenghat T, Hong CI, Papin JA, Moore SR. Fawad JA, et al. Gastroenterology. 2022 Nov;163(5):1377-1390.e11. doi: 10.1053/j.gastro.2022.07.051. Epub 2022 Aug 4. Gastroenterology. 2022. PMID: 35934064
Epithelial sensing of microbiota-derived signals.
Eshleman EM, Alenghat T. Eshleman EM, et al. Genes Immun. 2021 Oct;22(5-6):237-246. doi: 10.1038/s41435-021-00124-w. Epub 2021 Apr 6. Genes Immun. 2021. PMID: 33824498 Free PMC article. Review.
Microbiota-derived metabolite promotes HDAC3 activity in the gut.
Wu SE, Hashimoto-Hill S, Woo V, Eshleman EM, Whitt J, Engleman L, Karns R, Denson LA, Haslam DB, Alenghat T. Wu SE, et al. Nature. 2020 Oct;586(7827):108-112. doi: 10.1038/s41586-020-2604-2. Epub 2020 Jul 30. Nature. 2020. PMID: 32731255 Free PMC article.