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Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2.
Cell Rep. 2022 Oct 25;41(4):111505. doi: 10.1016/j.celrep.2022.111505.
Cell Rep. 2022.
PMID: 36288715
Free PMC article.
Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2.
Kim G, Nakayama L, Blum JA, Akiyama T, Boeynaems S, Chakraborty M, Couthouis J, Tassoni-Tsuchida E, Rodriguez CM, Bassik MC, Gitler AD.
Kim G, et al.
Cell Rep. 2022 Oct 25;41(4):111508. doi: 10.1016/j.celrep.2022.111508.
Cell Rep. 2022.
PMID: 36288714
Free PMC article.
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