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An endogenous opioid circuit determines state-dependent reward consumption.
Castro DC, Oswell CS, Zhang ET, Pedersen CE, Piantadosi SC, Rossi MA, Hunker AC, Guglin A, Morón JA, Zweifel LS, Stuber GD, Bruchas MR. Castro DC, et al. Nature. 2021 Oct;598(7882):646-651. doi: 10.1038/s41586-021-04013-0. Epub 2021 Oct 13. Nature. 2021. PMID: 34646022 Free PMC article.
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement.
Al-Hasani R, Gowrishankar R, Schmitz GP, Pedersen CE, Marcus DJ, Shirley SE, Hobbs TE, Elerding AJ, Renaud SJ, Jing M, Li Y, Alvarez VA, Lemos JC, Bruchas MR. Al-Hasani R, et al. Nat Neurosci. 2021 Oct;24(10):1414-1428. doi: 10.1038/s41593-021-00898-2. Epub 2021 Aug 12. Nat Neurosci. 2021. PMID: 34385700 Free PMC article.