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Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT2C Receptor and Dual 5-HT2C/5-HT2A Receptor Modulators.
Chen J, Garcia EJ, Merritt CR, Zamora JC, Bolinger AA, Pazdrak K, Stafford SJ, Mifflin RC, Wold EA, Wild CT, Chen H, Anastasio NC, Cunningham KA, Zhou J. Chen J, et al. J Med Chem. 2023 Jul 27;66(14):9992-10009. doi: 10.1021/acs.jmedchem.3c00908. Epub 2023 Jul 18. J Med Chem. 2023. PMID: 37462530 Free PMC article.
BH4 domain of Bcl-2 as a novel target for cancer therapy.
Liu Z, Wild C, Ding Y, Ye N, Chen H, Wold EA, Zhou J. Liu Z, et al. Drug Discov Today. 2016 Jun;21(6):989-96. doi: 10.1016/j.drudis.2015.11.008. Epub 2015 Nov 26. Drug Discov Today. 2016. PMID: 26631752 Free PMC article. Review.
Direct Activation of Bax Protein for Cancer Therapy.
Liu Z, Ding Y, Ye N, Wild C, Chen H, Zhou J. Liu Z, et al. Med Res Rev. 2016 Mar;36(2):313-41. doi: 10.1002/med.21379. Epub 2015 Sep 23. Med Res Rev. 2016. PMID: 26395559 Free PMC article. Review.