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Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity.
Haematologica. 2023 Sep 1;108(9):2343-2357. doi: 10.3324/haematol.2022.281894.
Haematologica. 2023.
PMID: 37021547
Free PMC article.
Extinguishing the Embers: Targeting AML Metabolism.
Culp-Hill R, D'Alessandro A, Pietras EM.
Culp-Hill R, et al.
Trends Mol Med. 2021 Apr;27(4):332-344. doi: 10.1016/j.molmed.2020.10.001. Epub 2020 Oct 26.
Trends Mol Med. 2021.
PMID: 33121874
Free PMC article.
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