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Year Number of Results
2015 1
2016 3
2017 2
2018 2
2019 3
2022 1
2023 1
2024 0

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12 results

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Page 1
A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.
Soto-Feliciano YM, Sánchez-Rivera FJ, Perner F, Barrows DW, Kastenhuber ER, Ho YJ, Carroll T, Xiong Y, Anand D, Soshnev AA, Gates L, Beytagh MC, Cheon D, Gu S, Liu XS, Krivtsov AV, Meneses M, de Stanchina E, Stone RM, Armstrong SA, Lowe SW, Allis CD. Soto-Feliciano YM, et al. Cancer Discov. 2023 Jan 9;13(1):146-169. doi: 10.1158/2159-8290.CD-22-0416. Cancer Discov. 2023. PMID: 36264143 Free PMC article.
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Sánchez-Rivera FJ, Diaz BJ, Kastenhuber ER, Schmidt H, Katti A, Kennedy M, Tem V, Ho YJ, Leibold J, Paffenholz SV, Barriga FM, Chu K, Goswami S, Wuest AN, Simon JM, Tsanov KM, Chakravarty D, Zhang H, Leslie CS, Lowe SW, Dow LE. Sánchez-Rivera FJ, et al. Nat Biotechnol. 2022 Jun;40(6):862-873. doi: 10.1038/s41587-021-01172-3. Epub 2022 Feb 14. Nat Biotechnol. 2022. PMID: 35165384 Free PMC article.
Road map for fibrolamellar carcinoma: progress and goals of a diversified approach.
Kastenhuber ER, Craig J, Ramsey J, Sullivan KM, Sage J, de Oliveira S, Riehle KJ, Scott JD, Gordan JD, Bardeesy N, Abou-Alfa GK. Kastenhuber ER, et al. J Hepatocell Carcinoma. 2019 Jan 31;6:41-48. doi: 10.2147/JHC.S194764. eCollection 2019. J Hepatocell Carcinoma. 2019. PMID: 30951568 Free PMC article.
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.
Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP 4th, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D'Alessandro A, Lowe SW, Prives C. Moon SH, et al. Cell. 2019 Jan 24;176(3):564-580.e19. doi: 10.1016/j.cell.2018.11.011. Epub 2018 Dec 20. Cell. 2019. PMID: 30580964 Free PMC article.
Optimized base editors enable efficient editing in cells, organoids and mice.
Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE. Zafra MP, et al. Nat Biotechnol. 2018 Oct;36(9):888-893. doi: 10.1038/nbt.4194. Epub 2018 Jul 3. Nat Biotechnol. 2018. PMID: 29969439 Free PMC article.
DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma.
Kastenhuber ER, Lalazar G, Houlihan SL, Tschaharganeh DF, Baslan T, Chen CC, Requena D, Tian S, Bosbach B, Wilkinson JE, Simon SM, Lowe SW. Kastenhuber ER, et al. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13076-13084. doi: 10.1073/pnas.1716483114. Epub 2017 Nov 21. Proc Natl Acad Sci U S A. 2017. PMID: 29162699 Free PMC article.
Putting p53 in Context.
Kastenhuber ER, Lowe SW. Kastenhuber ER, et al. Cell. 2017 Sep 7;170(6):1062-1078. doi: 10.1016/j.cell.2017.08.028. Cell. 2017. PMID: 28886379 Free PMC article. Review.
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.
Liu Y, Chen C, Xu Z, Scuoppo C, Rillahan CD, Gao J, Spitzer B, Bosbach B, Kastenhuber ER, Baslan T, Ackermann S, Cheng L, Wang Q, Niu T, Schultz N, Levine RL, Mills AA, Lowe SW. Liu Y, et al. Nature. 2016 Mar 24;531(7595):471-475. doi: 10.1038/nature17157. Epub 2016 Mar 16. Nature. 2016. PMID: 26982726 Free PMC article.
12 results