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Gene Interactions in Human Disease Studies-Evidence Is Mounting.
Singhal P, Verma SS, Ritchie MD. Singhal P, et al. Annu Rev Biomed Data Sci. 2023 Aug 10;6:377-395. doi: 10.1146/annurev-biodatasci-102022-120818. Epub 2023 May 17. Annu Rev Biomed Data Sci. 2023. PMID: 37196359 Free article. Review.
Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets.
Singhal P, Veturi Y, Dudek SM, Lucas A, Frase A, van Steen K, Schrodi SJ, Fasel D, Weng C, Pendergrass R, Schaid DJ, Kullo IJ, Dikilitas O, Sleiman PMA, Hakonarson H, Moore JH, Williams SM, Ritchie MD, Verma SS. Singhal P, et al. Am J Hum Genet. 2023 Apr 6;110(4):575-591. doi: 10.1016/j.ajhg.2023.03.007. Am J Hum Genet. 2023. PMID: 37028392 Free PMC article.
Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure.
Levin MG, Tsao NL, Singhal P, Liu C, Vy HMT, Paranjpe I, Backman JD, Bellomo TR, Bone WP, Biddinger KJ, Hui Q, Dikilitas O, Satterfield BA, Yang Y, Morley MP, Bradford Y, Burke M, Reza N, Charest B; Regeneron Genetics Center; Judy RL, Puckelwartz MJ, Hakonarson H, Khan A, Kottyan LC, Kullo I, Luo Y, McNally EM, Rasmussen-Torvik LJ, Day SM, Do R, Phillips LS, Ellinor PT, Nadkarni GN, Ritchie MD, Arany Z, Cappola TP, Margulies KB, Aragam KG, Haggerty CM, Joseph J, Sun YV, Voight BF, Damrauer SM. Levin MG, et al. Nat Commun. 2022 Nov 14;13(1):6914. doi: 10.1038/s41467-022-34216-6. Nat Commun. 2022. PMID: 36376295 Free PMC article.
Schizophrenia Imaging Signatures and Their Associations With Cognition, Psychopathology, and Genetics in the General Population.
Chand GB, Singhal P, Dwyer DB, Wen J, Erus G, Doshi J, Srinivasan D, Mamourian E, Varol E, Sotiras A, Hwang G, Dazzan P, Kahn RS, Schnack HG, Zanetti MV, Meisenzahl E, Busatto GF, Crespo-Facorro B, Pantelis C, Wood SJ, Zhuo C, Shinohara RT, Shou H, Fan Y, Koutsouleris N, Kaczkurkin AN, Moore TM, Verma A, Calkins ME, Gur RE, Gur RC, Ritchie MD, Satterthwaite TD, Wolf DH, Davatzikos C. Chand GB, et al. Am J Psychiatry. 2022 Sep;179(9):650-660. doi: 10.1176/appi.ajp.21070686. Epub 2022 Apr 12. Am J Psychiatry. 2022. PMID: 35410495 Free PMC article.