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HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia.
Dong Q, Xiu Y, Wang Y, Hodgson C, Borcherding N, Jordan C, Buchanan J, Taylor E, Wagner B, Leidinger M, Holman C, Thiele DJ, O'Brien S, Xue HH, Zhao J, Li Q, Meyerson H, Boyce BF, Zhao C. Dong Q, et al. Nat Commun. 2022 Oct 16;13(1):6107. doi: 10.1038/s41467-022-33861-1. Nat Commun. 2022. PMID: 36245043 Free PMC article.
Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102.
Brashears CB, Prudner BC, Rathore R, Caldwell KE, Dehner CA, Buchanan JL, Lange SES, Poulin N, Sehn JK, Roszik J, Spitzer D, Jones KB, O'Keefe R, Nielsen TO, Taylor EB, Held JM, Hawkins W, Van Tine BA. Brashears CB, et al. Clin Cancer Res. 2022 Aug 15;28(16):3573-3589. doi: 10.1158/1078-0432.CCR-22-0470. Clin Cancer Res. 2022. PMID: 35421237 Free PMC article.