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Long-term enhancements in antidepressant efficacy and neurogenesis: Effects of intranasal co-administration of neuropeptide Y 1 receptor (NPY1R) and galanin receptor 2 (GALR2) agonists in the ventral hippocampus.
Beltran-Casanueva R, Hernández-García A, Serrano-Castro PJ, Sánchez-Pérez JA, Barbancho-Fernández MA, García-Casares N, Fuxe K, Borroto-Escuela DO, Narváez M. Beltran-Casanueva R, et al. FASEB J. 2024 Apr 15;38(7):e23595. doi: 10.1096/fj.202400087R. FASEB J. 2024. PMID: 38572811
Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions.
Sánchez-Varo R, López-Salas A, Beltran-Casanueva R, Díaz-Sánchez E, Alvarez-Contino JE, Barbancho-Fernández MA, Serrano-Castro P, Fuxe K, Borroto-Escuela DO, García-Casares N, Narváez M. Sánchez-Varo R, et al. Behav Brain Funct. 2024 Mar 28;20(1):6. doi: 10.1186/s12993-024-00230-5. Behav Brain Funct. 2024. PMID: 38549164 Free PMC article.
The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease.
Romero-Fernandez W, Taura JJ, Crans RAJ, Lopez-Cano M, Fores-Pons R, Narváez M, Carlsson J, Ciruela F, Fuxe K, Borroto-Escuela DO. Romero-Fernandez W, et al. Mol Neurobiol. 2022 Oct;59(10):5955-5969. doi: 10.1007/s12035-022-02946-9. Epub 2022 Jul 12. Mol Neurobiol. 2022. PMID: 35829830 Free PMC article.
The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons.
Borroto-Escuela DO, Ferraro L, Beggiato S, Narváez M, Fores-Pons R, Alvarez-Contino JE, Wydra K, Frankowska M, Bader M, Filip M, Fuxe K. Borroto-Escuela DO, et al. Pharmacol Rep. 2021 Aug;73(4):1096-1108. doi: 10.1007/s43440-021-00314-3. Epub 2021 Aug 24. Pharmacol Rep. 2021. PMID: 34426901 Free PMC article. Review.
The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects.
Borroto-Escuela DO, Ambrogini P, Chruścicka B, Lindskog M, Crespo-Ramirez M, Hernández-Mondragón JC, Perez de la Mora M, Schellekens H, Fuxe K. Borroto-Escuela DO, et al. Int J Mol Sci. 2021 Feb 15;22(4):1927. doi: 10.3390/ijms22041927. Int J Mol Sci. 2021. PMID: 33672070 Free PMC article. Review.