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The natural product vioprolide A exerts anti-inflammatory actions through inhibition of its cellular target NOP14 and downregulation of importin-dependent NF-ĸB p65 nuclear translocation.
Burgers LD, Luong B, Li Y, Fabritius MP, Michalakis S, Reichel CA, Müller R, Fürst R. Burgers LD, et al. Among authors: furst r. Biomed Pharmacother. 2021 Dec;144:112255. doi: 10.1016/j.biopha.2021.112255. Epub 2021 Oct 2. Biomed Pharmacother. 2021. PMID: 34607110 Free article.
Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.
Proschak A, Martinelli G, Frank D, Rotter MJ, Brunst S, Weizel L, Burgers LD, Fürst R, Proschak E, Sosič I, Gobec S, Wichelhaus TA. Proschak A, et al. Among authors: furst r. Eur J Med Chem. 2022 Jan 15;228:113975. doi: 10.1016/j.ejmech.2021.113975. Epub 2021 Nov 13. Eur J Med Chem. 2022. PMID: 34865870
Designing a Small Fluorescent Inhibitor to Investigate Soluble Epoxide Hydrolase Engagement in Living Cells.
Brunst S, Schönfeld J, Breunig P, Burgers LD, DeMeglio M, Ehrler JHM, Lillich FF, Weizel L, Hefendehl JK, Fürst R, Proschak E, Hiesinger K. Brunst S, et al. Among authors: furst r. ACS Med Chem Lett. 2022 Jun 14;13(7):1062-1067. doi: 10.1021/acsmedchemlett.2c00073. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859883 Free PMC article.
154 results