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Allyl Isothiocyanate (AITC) Induces Apoptotic Cell Death In Vitro and Exhibits Anti-Tumor Activity in a Human Glioblastoma GBM8401/luc2 Model.
Lu KW, Lu TJ, Chueh FS, Lai KC, Hsia TC, Peng SF, Cheng CC, Chou YC, Hsu FT. Lu KW, et al. Int J Mol Sci. 2022 Sep 8;23(18):10411. doi: 10.3390/ijms231810411. Int J Mol Sci. 2022. PMID: 36142326 Free PMC article.
Tumor tissues were examined for histopathological changes using H&E staining, and we analyzed the protein levels via immunohistochemical analysis. Our results indicate that AITC significantly inhibited tumor growth at both doses of AITC due to the reduction in t …
Tumor tissues were examined for histopathological changes using H&E staining, and we analyzed the protein levels via immunohistochemical …
Demethoxycurcumin Suppresses Human Brain Glioblastoma Multiforme GBM 8401 Cell Xenograft Tumor in Nude Mice In Vivo.
Huang YP, Ma YS, Kuo CL, Liao CL, Chen PY, Peng SF, Hsu FT, Lai KC. Huang YP, et al. Int J Mol Sci. 2021 May 23;22(11):5503. doi: 10.3390/ijms22115503. Int J Mol Sci. 2021. PMID: 34071132 Free PMC article.
The tumor volumes and weights in 60 mg/kg treatment of DMC were lower than that of 30 mg/kg. Immunohistochemical analysis was used to measure protein expression of tumors and results showed that DMC treatment led to lightly staining with anti-Bcl-2 and -XIAP and 60 mg/kg t …
The tumor volumes and weights in 60 mg/kg treatment of DMC were lower than that of 30 mg/kg. Immunohistochemical analysis was used to …
Mangiferin induces immune responses and evaluates the survival rate in WEHI-3 cell generated mouse leukemia in vivo.
Shang HS, Chen CJ, Shih YL, Peng SF, Chen YL, Liu KC, Huang HC, Hsueh SC, Chen KW, Lu HF, Lee MH, Lee MZ, Lu KW. Shang HS, et al. Environ Toxicol. 2021 Jan;36(1):77-85. doi: 10.1002/tox.23013. Epub 2020 Sep 5. Environ Toxicol. 2021. PMID: 32889744
In the present study, we investigated the effects of mangiferin on leukemia WEHI-3 cell generated leukemia BLAB/c mice. Overall, the experiments were divided into two parts, one part was immune responses experiment and the other was the survival rate exper …
In the present study, we investigated the effects of mangiferin on leukemia WEHI-3 cell generated leukemia BLAB/c mice. Overall, the expe …
Ouabain promotes immune responses in WEHI-3 cells to generate leukemia mice through enhancing phagocytosis and natural killer cell activities in vivo.
Shih YL, Shang HS, Chen YL, Hsueh SC, Chou HM, Lu HF, Lee MZ, Hou HT, Chuang YY, Lee MH, Chen KW, Chung JG. Shih YL, et al. Environ Toxicol. 2019 May;34(5):659-665. doi: 10.1002/tox.22732. Epub 2019 Feb 13. Environ Toxicol. 2019. PMID: 30761740
However, there are no reports to show the effects on immune responses in a leukemia mouse model. In this study, WEHI-3 cell generated leukemia mice were developed and treated by oral ouabain at 0, 0.75, 1.5, and 3 mg/kg for 15 days. ...
However, there are no reports to show the effects on immune responses in a leukemia mouse model. In this study, WEHI-3 cell generated leukem …
Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells.
Chou YC, Chang MY, Lee HT, Shen CC, Harnod T, Liang YJ, Wu RS, Lai KC, Hsu FT, Chung JG. Chou YC, et al. Molecules. 2018 Sep 10;23(9):2305. doi: 10.3390/molecules23092305. Molecules. 2018. PMID: 30201893 Free PMC article.
Phenethyl isothiocyanate (PEITC) from cruciferous vegetables can inhibit the growth of various human cancer cells. In previous studies, we determined that PEITC inhibited the in vitro growth of human glioblastoma GBM 8401 cells by inducing apoptosis, inhibiting migr …
Phenethyl isothiocyanate (PEITC) from cruciferous vegetables can inhibit the growth of various human cancer cells. In previous studie …