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Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
Krebs A, Waldmann T, Wilks MF, Van Vugt-Lussenburg BMA, Van der Burg B, Terron A, Steger-Hartmann T, Ruegg J, Rovida C, Pedersen E, Pallocca G, Luijten M, Leite SB, Kustermann S, Kamp H, Hoeng J, Hewitt P, Herzler M, Hengstler JG, Heinonen T, Hartung T, Hardy B, Gantner F, Fritsche E, Fant K, Ezendam J, Exner T, Dunkern T, Dietrich DR, Coecke S, Busquet F, Braeuning A, Bondarenko O, Bennekou SH, Beilmann M, Leist M. Krebs A, et al. Among authors: exner t. ALTEX. 2019;36(4):682-699. doi: 10.14573/altex.1909271. ALTEX. 2019. PMID: 31658359 Free article.
Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
Krebs A, Waldmann T, Wilks MF, Van Vugt-Lussenburg BMA, Van der Burg B, Terron A, Steger-Hartmann T, Ruegg J, Rovida C, Pedersen E, Pallocca G, Luijten M, Leite SB, Kustermann S, Kamp H, Hoeng J, Hewitt P, Herzler M, Hengstler JG, Heinonen T, Hartung T, Hardy B, Gantner F, Fritsche E, Fant K, Ezendam J, Exner T, Dunkern T, Dietrich DR, Coecke S, Busquet F, Braeuning A, Bondarenko O, Bennekou SH, Beilmann M, Leist M. Krebs A, et al. Among authors: exner t. ALTEX. 2020;37(1):164. doi: 10.14573/altex.1909271e. ALTEX. 2020. PMID: 31960940 Free article.
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.
Krebs A, van Vugt-Lussenburg BMA, Waldmann T, Albrecht W, Boei J, Ter Braak B, Brajnik M, Braunbeck T, Brecklinghaus T, Busquet F, Dinnyes A, Dokler J, Dolde X, Exner TE, Fisher C, Fluri D, Forsby A, Hengstler JG, Holzer AK, Janstova Z, Jennings P, Kisitu J, Kobolak J, Kumar M, Limonciel A, Lundqvist J, Mihalik B, Moritz W, Pallocca G, Ulloa APC, Pastor M, Rovida C, Sarkans U, Schimming JP, Schmidt BZ, Stöber R, Strassfeld T, van de Water B, Wilmes A, van der Burg B, Verfaillie CM, von Hellfeld R, Vrieling H, Vrijenhoek NG, Leist M. Krebs A, et al. Among authors: exner te. Arch Toxicol. 2020 Jul;94(7):2435-2461. doi: 10.1007/s00204-020-02802-6. Epub 2020 Jul 6. Arch Toxicol. 2020. PMID: 32632539 Free PMC article.
Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.
Escher SE, Aguayo-Orozco A, Benfenati E, Bitsch A, Braunbeck T, Brotzmann K, Bois F, van der Burg B, Castel J, Exner T, Gadaleta D, Gardner I, Goldmann D, Hatley O, Golbamaki N, Graepel R, Jennings P, Limonciel A, Long A, Maclennan R, Mombelli E, Norinder U, Jain S, Capinha LS, Taboureau OT, Tolosa L, Vrijenhoek NG, van Vugt-Lussenburg BMA, Walker P, van de Water B, Wehr M, White A, Zdrazil B, Fisher C. Escher SE, et al. Among authors: exner t. Toxicol In Vitro. 2022 Mar;79:105269. doi: 10.1016/j.tiv.2021.105269. Epub 2021 Oct 29. Toxicol In Vitro. 2022. PMID: 34757180 Free article.
Towards a qAOP framework for predictive toxicology - Linking data to decisions.
Paini A, Campia I, Cronin MTD, Asturiol D, Ceriani L, Exner TE, Gao W, Gomes C, Kruisselbrink J, Martens M, Meek MEB, Pamies D, Pletz J, Scholz S, Schüttler A, Spînu N, Villeneuve DL, Wittwehr C, Worth A, Luijten M. Paini A, et al. Among authors: exner te. Comput Toxicol. 2022 Feb;21:100195. doi: 10.1016/j.comtox.2021.100195. Comput Toxicol. 2022. PMID: 35211660 Free PMC article.
Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models.
Oki NO, Farcal L, Abdelaziz A, Florean O, Doktorova TY, Exner T, Kohonen P, Grafström R, Hardy B. Oki NO, et al. Among authors: exner t. Toxicol In Vitro. 2019 Feb;54:23-32. doi: 10.1016/j.tiv.2018.09.002. Epub 2018 Sep 7. Toxicol In Vitro. 2019. PMID: 30196099 Free article.
243 results