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Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies.
Pons D, Trompet S, de Craen AJ, Thijssen PE, Quax PH, de Vries MR, Wierda RJ, van den Elsen PJ, Monraats PS, Ewing MM, Heijmans BT, Slagboom PE, Zwinderman AH, Doevendans PA, Tio RA, de Winter RJ, de Maat MP, Iakoubova OA, Sattar N, Shepherd J, Westendorp RG, Jukema JW; PROSPER study group; WOSCOPS study group; GENDER study group. Pons D, et al. Among authors: ewing mm. Heart. 2011 Jan;97(2):143-50. doi: 10.1136/hrt.2010.199927. Epub 2010 Nov 8. Heart. 2011. PMID: 21062767
Matrix metalloproteinases 2 and 3 gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention: Is there still room for determining genetic variation of MMPs for assessment of an increased risk of restenosis?
Verschuren JJ, Sampietro ML, Pons D, Trompet S, Ewing MM, Quax PH, de Knijff P, Zwinderman AH, de Winter RJ, Tio RA, de Maat MP, Doevendans PA, Jukema JW. Verschuren JJ, et al. Among authors: ewing mm. Dis Markers. 2010;29(5):265-73. doi: 10.3233/DMA-2010-0757. Dis Markers. 2010. PMID: 21206012 Free PMC article.
Blocking toll-like receptors 7 and 9 reduces postinterventional remodeling via reduced macrophage activation, foam cell formation, and migration.
Karper JC, Ewing MM, Habets KL, de Vries MR, Peters EA, van Oeveren-Rietdijk AM, de Boer HC, Hamming JF, Kuiper J, Kandimalla ER, La Monica N, Jukema JW, Quax PH. Karper JC, et al. Among authors: ewing mm. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):e72-80. doi: 10.1161/ATVBAHA.112.249391. Epub 2012 May 24. Arterioscler Thromb Vasc Biol. 2012. PMID: 22628437
Lysine acetyltransferase PCAF is a key regulator of arteriogenesis.
Bastiaansen AJ, Ewing MM, de Boer HC, van der Pouw Kraan TC, de Vries MR, Peters EA, Welten SM, Arens R, Moore SM, Faber JE, Jukema JW, Hamming JF, Nossent AY, Quax PH. Bastiaansen AJ, et al. Among authors: ewing mm. Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1902-10. doi: 10.1161/ATVBAHA.113.301579. Epub 2013 Jun 20. Arterioscler Thromb Vasc Biol. 2013. PMID: 23788761 Free PMC article.
TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation.
Karper JC, Ewing MM, de Vries MR, de Jager SC, Peters EA, de Boer HC, van Zonneveld AJ, Kuiper J, Huizinga EG, Brondijk TH, Jukema JW, Quax PH. Karper JC, et al. Among authors: ewing mm. PLoS One. 2013 Jul 2;8(7):e67923. doi: 10.1371/journal.pone.0067923. Print 2013. PLoS One. 2013. PMID: 23844130 Free PMC article.
An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation.
Karper JC, de Jager SC, Ewing MM, de Vries MR, Bot I, van Santbrink PJ, Redeker A, Mallat Z, Binder CJ, Arens R, Jukema JW, Kuiper J, Quax PH. Karper JC, et al. Among authors: ewing mm. Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2810-7. doi: 10.1161/ATVBAHA.113.301882. Epub 2013 Oct 10. Arterioscler Thromb Vasc Biol. 2013. PMID: 24115036
23 results