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Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties.
Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Urs NM, et al. Among authors: evron t. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8178-E8186. doi: 10.1073/pnas.1614347113. Epub 2016 Dec 1. Proc Natl Acad Sci U S A. 2016. PMID: 27911814 Free PMC article.
Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds.
Bruni G, Rennekamp AJ, Velenich A, McCarroll M, Gendelev L, Fertsch E, Taylor J, Lakhani P, Lensen D, Evron T, Lorello PJ, Huang XP, Kolczewski S, Carey G, Caldarone BJ, Prinssen E, Roth BL, Keiser MJ, Peterson RT, Kokel D. Bruni G, et al. Among authors: evron t. Nat Chem Biol. 2016 Jul;12(7):559-66. doi: 10.1038/nchembio.2097. Epub 2016 May 30. Nat Chem Biol. 2016. PMID: 27239787 Free PMC article.
ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse.
Barak LS, Bai Y, Peterson S, Evron T, Urs NM, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, Caron MG. Barak LS, et al. Among authors: evron t. ACS Chem Biol. 2016 Jul 15;11(7):1880-90. doi: 10.1021/acschembio.6b00291. Epub 2016 May 5. ACS Chem Biol. 2016. PMID: 27119457 Free PMC article.
G Protein and β-arrestin signaling bias at the ghrelin receptor.
Evron T, Peterson SM, Urs NM, Bai Y, Rochelle LK, Caron MG, Barak LS. Evron T, et al. J Biol Chem. 2014 Nov 28;289(48):33442-55. doi: 10.1074/jbc.M114.581397. Epub 2014 Sep 26. J Biol Chem. 2014. PMID: 25261469 Free PMC article.
The role of arrestins in development.
Philipp M, Evron T, Caron MG. Philipp M, et al. Among authors: evron t. Prog Mol Biol Transl Sci. 2013;118:225-42. doi: 10.1016/B978-0-12-394440-5.00009-7. Prog Mol Biol Transl Sci. 2013. PMID: 23764056 Review.
23 results