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Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist.
Bossart M, Wagner M, Elvert R, Evers A, Hübschle T, Kloeckener T, Lorenz K, Moessinger C, Eriksson O, Velikyan I, Pierrou S, Johansson L, Dietert G, Dietz-Baum Y, Kissner T, Nowotny I, Einig C, Jan C, Rharbaoui F, Gassenhuber J, Prochnow HP, Agueusop I, Porksen N, Smith WB, Nitsche A, Konkar A. Bossart M, et al. Among authors: evers a. Cell Metab. 2022 Jan 4;34(1):59-74.e10. doi: 10.1016/j.cmet.2021.12.005. Epub 2021 Dec 20. Cell Metab. 2022. PMID: 34932984 Free article.
Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates.
Elvert R, Herling AW, Bossart M, Weiss T, Zhang B, Wenski P, Wandschneider J, Kleutsch S, Butty U, Kannt A, Wagner M, Haack T, Evers A, Dudda A, Lorenz M, Keil S, Larsen PJ. Elvert R, et al. Among authors: evers a. Diabetes Obes Metab. 2018 Aug;20(8):1836-1851. doi: 10.1111/dom.13212. Epub 2018 Jun 25. Diabetes Obes Metab. 2018. PMID: 29938884 Free PMC article.
First-in-class positron emission tomography tracer for the glucagon receptor.
Velikyan I, Haack T, Bossart M, Evers A, Laitinen I, Larsen P, Plettenburg O, Johansson L, Pierrou S, Wagner M, Eriksson O. Velikyan I, et al. Among authors: evers a. EJNMMI Res. 2019 Feb 15;9(1):17. doi: 10.1186/s13550-019-0482-0. EJNMMI Res. 2019. PMID: 30771019 Free PMC article.
Incretin combination therapy for the treatment of non-alcoholic steatohepatitis.
Kannt A, Madsen AN, Kammermeier C, Elvert R, Klöckener T, Bossart M, Haack T, Evers A, Lorenz K, Hennerici W, Rocher C, Böcskei Z, Guillemot JC, Mikol V, Pattou F, Staels B, Wagner M. Kannt A, et al. Among authors: evers a. Diabetes Obes Metab. 2020 Aug;22(8):1328-1338. doi: 10.1111/dom.14035. Epub 2020 Apr 12. Diabetes Obes Metab. 2020. PMID: 32196896
617 results