Evans RJ - Search Results

1

P2X1 ion channel deficiency causes massive bleeding in inflamed intestine and increases thrombosis.

Wéra O, Lecut C, Servais L, Hego A, Delierneux C, Jiang Z, Keutgens A, Evans RJ, Delvenne P, Lancellotti P, Oury C. Wéra O, et al. Among authors: evans rj. J Thromb Haemost. 2020 Jan;18(1):44-56. doi: 10.1111/jth.14620. Epub 2019 Sep 10. J Thromb Haemost. 2020. PMID: 31448510 Free article.

2

P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice.

Darbousset R, Delierneux C, Mezouar S, Hego A, Lecut C, Guillaumat I, Riederer MA, Evans RJ, Dignat-George F, Panicot-Dubois L, Oury C, Dubois C. Darbousset R, et al. Among authors: evans rj. Blood. 2014 Oct 16;124(16):2575-85. doi: 10.1182/blood-2014-04-571679. Epub 2014 Aug 22. Blood. 2014. PMID: 25150292 Free PMC article.

3

P2X1 ion channels promote neutrophil chemotaxis through Rho kinase activation.

Lecut C, Frederix K, Johnson DM, Deroanne C, Thiry M, Faccinetto C, Marée R, Evans RJ, Volders PG, Bours V, Oury C. Lecut C, et al. Among authors: evans rj. J Immunol. 2009 Aug 15;183(4):2801-9. doi: 10.4049/jimmunol.0804007. Epub 2009 Jul 27. J Immunol. 2009. PMID: 19635923 Free article.

4

Amplification of human platelet activation by surface pannexin-1 channels.

Taylor KA, Wright JR, Vial C, Evans RJ, Mahaut-Smith MP. Taylor KA, et al. Among authors: evans rj. J Thromb Haemost. 2014 Jun;12(6):987-98. doi: 10.1111/jth.12566. J Thromb Haemost. 2014. PMID: 24655807 Free PMC article.

5

Ca2+ influx through P2X1 receptors amplifies P2Y1 receptor-evoked Ca2+ signaling and ADP-evoked platelet aggregation.

Jones S, Evans RJ, Mahaut-Smith MP. Jones S, et al. Among authors: evans rj. Mol Pharmacol. 2014 Sep;86(3):243-51. doi: 10.1124/mol.114.092528. Epub 2014 Jun 12. Mol Pharmacol. 2014. PMID: 24923466 Free article.

6

Development of a P2X1-eYFP receptor knock-in mouse to track receptors in real time.

Mahaut Smith MP, Evans RJ, Vial C. Mahaut Smith MP, et al. Among authors: evans rj. Purinergic Signal. 2019 Sep;15(3):397-402. doi: 10.1007/s11302-019-09666-1. Epub 2019 Jul 8. Purinergic Signal. 2019. PMID: 31286385 Free PMC article.

7

Kinetics of conformational changes revealed by voltage-clamp fluorometry give insight to desensitization at ATP-gated human P2X1 receptors.

Fryatt AG, Evans RJ. Fryatt AG, et al. Among authors: evans rj. Mol Pharmacol. 2014 Dec;86(6):707-15. doi: 10.1124/mol.114.095307. Epub 2014 Oct 8. Mol Pharmacol. 2014. PMID: 25296688

8

Calcium Signalling through Ligand-Gated Ion Channels such as P2X1 Receptors in the Platelet and other Non-Excitable Cells.

Mahaut-Smith MP, Taylor KA, Evans RJ. Mahaut-Smith MP, et al. Among authors: evans rj. Adv Exp Med Biol. 2016;898:305-29. doi: 10.1007/978-3-319-26974-0_13. Adv Exp Med Biol. 2016. PMID: 27161234 Review.

9

The P2X1 receptor is required for neutrophil extravasation during lipopolysaccharide-induced lethal endotoxemia in mice.

Maître B, Magnenat S, Heim V, Ravanat C, Evans RJ, de la Salle H, Gachet C, Hechler B. Maître B, et al. Among authors: evans rj. J Immunol. 2015 Jan 15;194(2):739-49. doi: 10.4049/jimmunol.1401786. Epub 2014 Dec 5. J Immunol. 2015. PMID: 25480563

10

Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel.

Roberts JA, Allsopp RC, El Ajouz S, Vial C, Schmid R, Young MT, Evans RJ. Roberts JA, et al. Among authors: evans rj. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4663-7. doi: 10.1073/pnas.1201872109. Epub 2012 Mar 5. Proc Natl Acad Sci U S A. 2012. PMID: 22393010 Free PMC article.

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