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Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Smola M, Gutten O, Dejmek M, Kožíšek M, Evangelidis T, Tehrani ZA, Novotná B, Nencka R, Birkuš G, Rulíšek L, Boura E. Smola M, et al. Among authors: evangelidis t. Angew Chem Int Ed Engl. 2021 Apr 26;60(18):10172-10178. doi: 10.1002/anie.202016805. Epub 2021 Mar 24. Angew Chem Int Ed Engl. 2021. PMID: 33616279 Free PMC article.
Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Yperman K, Papageorgiou AC, Merceron R, De Munck S, Bloch Y, Eeckhout D, Jiang Q, Tack P, Grigoryan R, Evangelidis T, Van Leene J, Vincze L, Vandenabeele P, Vanhaecke F, Potocký M, De Jaeger G, Savvides SN, Tripsianes K, Pleskot R, Van Damme D. Yperman K, et al. Among authors: evangelidis t. Nat Commun. 2021 May 24;12(1):3050. doi: 10.1038/s41467-021-23314-6. Nat Commun. 2021. PMID: 34031427 Free PMC article.
De novo design of a non-local β-sheet protein with high stability and accuracy.
Marcos E, Chidyausiku TM, McShan AC, Evangelidis T, Nerli S, Carter L, Nivón LG, Davis A, Oberdorfer G, Tripsianes K, Sgourakis NG, Baker D. Marcos E, et al. Among authors: evangelidis t. Nat Struct Mol Biol. 2018 Nov;25(11):1028-1034. doi: 10.1038/s41594-018-0141-6. Epub 2018 Oct 29. Nat Struct Mol Biol. 2018. PMID: 30374087 Free PMC article.
Discovery of New Aminosubstituted Pyrrolopyrimidines with Antiproliferative Activity Against Breast Cancer Cells and Investigation of their Effect Towards the PI3Kα Enzyme.
Daniilides K, Lougiakis N, Evangelidis T, Kostakis IK, Pouli N, Marakos P, Mikros E, Skaltsounis AL, Bach S, Baratte B, Ruchaud S, Karamani V, Papafotika A, Christoforidis S, Argyros O, Kouvari E, Tamvakopoulos C. Daniilides K, et al. Among authors: evangelidis t. Anticancer Agents Med Chem. 2017;17(7):990-1002. doi: 10.2174/1871520616666161207143450. Anticancer Agents Med Chem. 2017. PMID: 27928955
11 results