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The histone demethylase Kdm6b regulates the maturation and cytotoxicity of TCRαβ+CD8αα+ intestinal intraepithelial lymphocytes.
Zhang H, Hu Y, Liu D, Liu Z, Xie N, Liu S, Zhang J, Jiang Y, Li C, Wang Q, Chen X, Ye D, Sun D, Zhai Y, Yan X, Liu Y, Chen CD, Huang X, Eugene Chin Y, Shi Y, Wu B, Zhang X. Zhang H, et al. Among authors: eugene chin y. Cell Death Differ. 2022 Jul;29(7):1349-1363. doi: 10.1038/s41418-021-00921-w. Epub 2022 Jan 9. Cell Death Differ. 2022. PMID: 34999729 Free PMC article.
Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development.
He J, Shangguan X, Zhou W, Cao Y, Zheng Q, Tu J, Hu G, Liang Z, Jiang C, Deng L, Wang S, Yang W, Zuo Y, Ma J, Cai R, Chen Y, Fan Q, Dong B, Xue W, Tan H, Qi Y, Gu J, Su B, Eugene Chin Y, Chen G, Wang Q, Wang T, Cheng J. He J, et al. Among authors: eugene chin y. Nat Commun. 2021 Jul 16;12(1):4371. doi: 10.1038/s41467-021-24619-2. Nat Commun. 2021. PMID: 34272364 Free PMC article.
Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses.
Jiang Y, Li C, Wu Q, An P, Huang L, Wang J, Chen C, Chen X, Zhang F, Ma L, Liu S, He H, Xie S, Sun Y, Liu H, Zhan Y, Tao Y, Liu Z, Sun X, Hu Y, Wang Q, Ye D, Zhang J, Zou S, Wang Y, Wei G, Liu Y, Shi Y, Eugene Chin Y, Hao Y, Wang F, Zhang X. Jiang Y, et al. Among authors: eugene chin y. Nat Commun. 2019 Jul 3;10(1):2935. doi: 10.1038/s41467-019-11002-5. Nat Commun. 2019. PMID: 31270335 Free PMC article.
Bcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis.
Chen X, Cao X, Sun X, Lei R, Chen P, Zhao Y, Jiang Y, Yin J, Chen R, Ye D, Wang Q, Liu Z, Liu S, Cheng C, Mao J, Hou Y, Wang M, Siebenlist U, Eugene Chin Y, Wang Y, Cao L, Hu G, Zhang X. Chen X, et al. Among authors: eugene chin y. Cell Death Dis. 2016 Dec 1;7(12):e2508. doi: 10.1038/cddis.2016.405. Cell Death Dis. 2016. PMID: 27906182 Free PMC article.