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127 results

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Page 1
The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages.
Brunner JS, Vogel A, Lercher A, Caldera M, Korosec A, Pühringer M, Hofmann M, Hajto A, Kieler M, Garrido LQ, Kerndl M, Kuttke M, Mesteri I, Górna MW, Kulik M, Dominiak PM, Brandon AE, Estevez E, Egan CL, Gruber F, Schweiger M, Menche J, Bergthaler A, Weichhart T, Klavins K, Febbraio MA, Sharif O, Schabbauer G. Brunner JS, et al. Among authors: estevez e. Nat Metab. 2020 Dec;2(12):1427-1442. doi: 10.1038/s42255-020-00311-5. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199895
Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice.
Whitham M, Pal M, Petzold T, Hjorth M, Egan CL, Brunner JS, Estevez E, Iliades P, Zivanovic B, Reibe S, Hughes WE, Findeisen M, Hidalgo J, Febbraio MA. Whitham M, et al. Among authors: estevez e. Am J Physiol Endocrinol Metab. 2019 Oct 1;317(4):E597-E604. doi: 10.1152/ajpendo.00206.2019. Epub 2019 Aug 6. Am J Physiol Endocrinol Metab. 2019. PMID: 31386565 Free article.
Treatment of type 2 diabetes with the designer cytokine IC7Fc.
Findeisen M, Allen TL, Henstridge DC, Kammoun H, Brandon AE, Baggio LL, Watt KI, Pal M, Cron L, Estevez E, Yang C, Kowalski GM, O'Reilly L, Egan C, Sun E, Thai LM, Krippner G, Adams TE, Lee RS, Grötzinger J, Garbers C, Risis S, Kraakman MJ, Mellet NA, Sligar J, Kimber ET, Young RL, Cowley MA, Bruce CR, Meikle PJ, Baldock PA, Gregorevic P, Biden TJ, Cooney GJ, Keating DJ, Drucker DJ, Rose-John S, Febbraio MA. Findeisen M, et al. Among authors: estevez e. Nature. 2019 Oct;574(7776):63-68. doi: 10.1038/s41586-019-1601-9. Epub 2019 Sep 25. Nature. 2019. PMID: 31554967
Skeletal muscle-specific overexpression of heat shock protein 72 improves skeletal muscle insulin-stimulated glucose uptake but does not alter whole body metabolism.
Marshall JPS, Estevez E, Kammoun HL, King EJ, Bruce CR, Drew BG, Qian H, Iliades P, Gregorevic P, Febbraio MA, Henstridge DC. Marshall JPS, et al. Among authors: estevez e. Diabetes Obes Metab. 2018 Aug;20(8):1928-1936. doi: 10.1111/dom.13319. Epub 2018 May 3. Diabetes Obes Metab. 2018. PMID: 29652108
Targeting gp130 to prevent inflammation and promote insulin action.
Kraakman MJ, Allen TL, Whitham M, Iliades P, Kammoun HL, Estevez E, Lancaster GI, Febbraio MA. Kraakman MJ, et al. Among authors: estevez e. Diabetes Obes Metab. 2013 Sep;15 Suppl 3:170-5. doi: 10.1111/dom.12170. Diabetes Obes Metab. 2013. PMID: 24003934 Review.
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.
Mauer J, Chaurasia B, Goldau J, Vogt MC, Ruud J, Nguyen KD, Theurich S, Hausen AC, Schmitz J, Brönneke HS, Estevez E, Allen TL, Mesaros A, Partridge L, Febbraio MA, Chawla A, Wunderlich FT, Brüning JC. Mauer J, et al. Among authors: estevez e. Nat Immunol. 2014 May;15(5):423-30. doi: 10.1038/ni.2865. Epub 2014 Mar 30. Nat Immunol. 2014. PMID: 24681566 Free PMC article.
Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance.
Kraakman MJ, Kammoun HL, Allen TL, Deswaerte V, Henstridge DC, Estevez E, Matthews VB, Neill B, White DA, Murphy AJ, Peijs L, Yang C, Risis S, Bruce CR, Du XJ, Bobik A, Lee-Young RS, Kingwell BA, Vasanthakumar A, Shi W, Kallies A, Lancaster GI, Rose-John S, Febbraio MA. Kraakman MJ, et al. Among authors: estevez e. Cell Metab. 2015 Mar 3;21(3):403-16. doi: 10.1016/j.cmet.2015.02.006. Cell Metab. 2015. PMID: 25738456 Free article.
Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise.
Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. Whitham M, et al. Among authors: estevez e. Cell Metab. 2018 Jan 9;27(1):237-251.e4. doi: 10.1016/j.cmet.2017.12.001. Cell Metab. 2018. PMID: 29320704 Free article. Clinical Trial.
127 results