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CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification.
Okoye AA, Duell DD, Fukazawa Y, Varco-Merth B, Marenco A, Behrens H, Chaunzwa M, Selseth AN, Gilbride RM, Shao J, Edlefsen PT, Geleziunas R, Pinkevych M, Davenport MP, Busman-Sahay K, Nekorchuk M, Park H, Smedley J, Axthelm MK, Estes JD, Hansen SG, Keele BF, Lifson JD, Picker LJ. Okoye AA, et al. Among authors: estes jd. J Clin Invest. 2021 Apr 15;131(8):e141677. doi: 10.1172/JCI141677. J Clin Invest. 2021. PMID: 33630764 Free PMC article.
A macaque model of HIV-1 infection.
Hatziioannou T, Ambrose Z, Chung NP, Piatak M Jr, Yuan F, Trubey CM, Coalter V, Kiser R, Schneider D, Smedley J, Pung R, Gathuka M, Estes JD, Veazey RS, KewalRamani VN, Lifson JD, Bieniasz PD. Hatziioannou T, et al. Among authors: estes jd. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4425-9. doi: 10.1073/pnas.0812587106. Epub 2009 Mar 2. Proc Natl Acad Sci U S A. 2009. PMID: 19255423 Free PMC article.
Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection.
Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M Jr, Roederer M, Lifson JD, Ott DE, Ohlen C. Minang JT, et al. Among authors: estes jd. J Immunol. 2010 Jan 1;184(1):315-26. doi: 10.4049/jimmunol.0902410. Epub 2009 Nov 30. J Immunol. 2010. PMID: 19949091 Free PMC article.
Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection.
Klatt NR, Harris LD, Vinton CL, Sung H, Briant JA, Tabb B, Morcock D, McGinty JW, Lifson JD, Lafont BA, Martin MA, Levine AD, Estes JD, Brenchley JM. Klatt NR, et al. Among authors: estes jd. Mucosal Immunol. 2010 Jul;3(4):387-98. doi: 10.1038/mi.2010.14. Epub 2010 Mar 31. Mucosal Immunol. 2010. PMID: 20357762 Free PMC article.
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.
Estes JD, Harris LD, Klatt NR, Tabb B, Pittaluga S, Paiardini M, Barclay GR, Smedley J, Pung R, Oliveira KM, Hirsch VM, Silvestri G, Douek DC, Miller CJ, Haase AT, Lifson J, Brenchley JM. Estes JD, et al. PLoS Pathog. 2010 Aug 19;6(8):e1001052. doi: 10.1371/journal.ppat.1001052. PLoS Pathog. 2010. PMID: 20808901 Free PMC article.
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.
Ortiz AM, Klatt NR, Li B, Yi Y, Tabb B, Hao XP, Sternberg L, Lawson B, Carnathan PM, Cramer EM, Engram JC, Little DM, Ryzhova E, Gonzalez-Scarano F, Paiardini M, Ansari AA, Ratcliffe S, Else JG, Brenchley JM, Collman RG, Estes JD, Derdeyn CA, Silvestri G. Ortiz AM, et al. Among authors: estes jd. J Clin Invest. 2011 Nov;121(11):4433-45. doi: 10.1172/JCI46023. Epub 2011 Oct 17. J Clin Invest. 2011. PMID: 22005304 Free PMC article.
227 results