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Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.
Perugorria MJ, Esparza-Baquer A, Oakley F, Labiano I, Korosec A, Jais A, Mann J, Tiniakos D, Santos-Laso A, Arbelaiz A, Gawish R, Sampedro A, Fontanellas A, Hijona E, Jimenez-Agüero R, Esterbauer H, Stoiber D, Bujanda L, Banales JM, Knapp S, Sharif O, Mann DA. Perugorria MJ, et al. Among authors: esterbauer h. Gut. 2019 Mar;68(3):533-546. doi: 10.1136/gutjnl-2017-314107. Epub 2018 Jan 27. Gut. 2019. PMID: 29374630 Free PMC article.
Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages.
Sharif O, Brunner JS, Korosec A, Martins R, Jais A, Snijder B, Vogel A, Caldera M, Hladik A, Lakovits K, Saluzzo S, Boehm B, Gorki AD, Mesteri I, Lindroos-Christensen J, Tillmann K, Stoiber D, Menche J, Schabbauer G, Bilban M, Superti-Furga G, Esterbauer H, Knapp S. Sharif O, et al. Among authors: esterbauer h. Diabetes. 2021 Sep;70(9):2042-2057. doi: 10.2337/db20-0572. Epub 2021 Feb 24. Diabetes. 2021. PMID: 33627323 Free PMC article.
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man.
Jais A, Einwallner E, Sharif O, Gossens K, Lu TT, Soyal SM, Medgyesi D, Neureiter D, Paier-Pourani J, Dalgaard K, Duvigneau JC, Lindroos-Christensen J, Zapf TC, Amann S, Saluzzo S, Jantscher F, Stiedl P, Todoric J, Martins R, Oberkofler H, Müller S, Hauser-Kronberger C, Kenner L, Casanova E, Sutterlüty-Fall H, Bilban M, Miller K, Kozlov AV, Krempler F, Knapp S, Lumeng CN, Patsch W, Wagner O, Pospisilik JA, Esterbauer H. Jais A, et al. Among authors: esterbauer h. Cell. 2014 Jul 3;158(1):25-40. doi: 10.1016/j.cell.2014.04.043. Cell. 2014. PMID: 24995976 Free PMC article.
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S. Martins R, et al. Among authors: esterbauer h. Nat Immunol. 2016 Dec;17(12):1361-1372. doi: 10.1038/ni.3590. Epub 2016 Oct 31. Nat Immunol. 2016. PMID: 27798618
Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis.
Todoric J, Strobl B, Jais A, Boucheron N, Bayer M, Amann S, Lindroos J, Teperino R, Prager G, Bilban M, Ellmeier W, Krempler F, Müller M, Wagner O, Patsch W, Pospisilik JA, Esterbauer H. Todoric J, et al. Among authors: esterbauer h. Diabetes. 2011 Jun;60(6):1668-76. doi: 10.2337/db10-1628. Epub 2011 May 2. Diabetes. 2011. PMID: 21536945 Free PMC article.
Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.
Stiedl P, McMahon R, Blaas L, Stanek V, Svinka J, Grabner B, Zollner G, Kessler SM, Claudel T, Müller M, Mikulits W, Bilban M, Esterbauer H, Eferl R, Haybaeck J, Trauner M, Casanova E. Stiedl P, et al. Among authors: esterbauer h. Hepatology. 2015 Feb;61(2):613-26. doi: 10.1002/hep.27408. Hepatology. 2015. PMID: 25179284 Free PMC article.
Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Mair M, Zollner G, Schneller D, Musteanu M, Fickert P, Gumhold J, Schuster C, Fuchsbichler A, Bilban M, Tauber S, Esterbauer H, Kenner L, Poli V, Blaas L, Kornfeld JW, Casanova E, Mikulits W, Trauner M, Eferl R. Mair M, et al. Among authors: esterbauer h. Gastroenterology. 2010 Jun;138(7):2499-508. doi: 10.1053/j.gastro.2010.02.049. Epub 2010 Feb 26. Gastroenterology. 2010. PMID: 20193684
301 results