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Epigenetic modifications and human disease.
Portela A, Esteller M. Portela A, et al. Among authors: esteller m. Nat Biotechnol. 2010 Oct;28(10):1057-68. doi: 10.1038/nbt.1685. Nat Biotechnol. 2010. PMID: 20944598 Review.
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. Fraga MF, et al. Among authors: esteller m. Nat Genet. 2005 Apr;37(4):391-400. doi: 10.1038/ng1531. Epub 2005 Mar 13. Nat Genet. 2005. PMID: 15765097
Epigenetic differences arise during the lifetime of monozygotic twins.
Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, Heine-Suñer D, Cigudosa JC, Urioste M, Benitez J, Boix-Chornet M, Sanchez-Aguilera A, Ling C, Carlsson E, Poulsen P, Vaag A, Stephan Z, Spector TD, Wu YZ, Plass C, Esteller M. Fraga MF, et al. Among authors: esteller m. Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10604-9. doi: 10.1073/pnas.0500398102. Epub 2005 Jul 11. Proc Natl Acad Sci U S A. 2005. PMID: 16009939 Free PMC article.
The necessity of a human epigenome project.
Esteller M. Esteller M. Carcinogenesis. 2006 Jun;27(6):1121-5. doi: 10.1093/carcin/bgl033. Epub 2006 May 13. Carcinogenesis. 2006. PMID: 16699174 Review.
752 results