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Enhanced T cell effector activity by targeting the Mediator kinase module.
Freitas KA, Belk JA, Sotillo E, Quinn PJ, Ramello MC, Malipatlolla M, Daniel B, Sandor K, Klysz D, Bjelajac J, Xu P, Burdsall KA, Tieu V, Duong VT, Donovan MG, Weber EW, Chang HY, Majzner RG, Espinosa JM, Satpathy AT, Mackall CL. Freitas KA, et al. Among authors: espinosa jm. Science. 2022 Nov 11;378(6620):eabn5647. doi: 10.1126/science.abn5647. Epub 2022 Nov 11. Science. 2022. PMID: 36356142 Free PMC article.
A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response.
Audetat KA, Galbraith MD, Odell AT, Lee T, Pandey A, Espinosa JM, Dowell RD, Taatjes DJ. Audetat KA, et al. Among authors: espinosa jm. Mol Cell Biol. 2017 Jun 15;37(13):e00626-16. doi: 10.1128/MCB.00626-16. Print 2017 Jul 1. Mol Cell Biol. 2017. PMID: 28416637 Free PMC article.
Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation.
Tatavosian R, Donovan MG, Galbraith MD, Duc HN, Szwarc MM, Joshi MU, Frieman A, Bilousova G, Cao Y, Smith KP, Song K, Rachubinski AL, Andrysik Z, Espinosa JM. Tatavosian R, et al. Among authors: espinosa jm. Cell Death Differ. 2023 Apr;30(4):952-965. doi: 10.1038/s41418-023-01113-4. Epub 2023 Jan 21. Cell Death Differ. 2023. PMID: 36681780 Free PMC article.
CDK8 Kinase Activity Promotes Glycolysis.
Galbraith MD, Andrysik Z, Pandey A, Hoh M, Bonner EA, Hill AA, Sullivan KD, Espinosa JM. Galbraith MD, et al. Among authors: espinosa jm. Cell Rep. 2017 Nov 7;21(6):1495-1506. doi: 10.1016/j.celrep.2017.10.058. Cell Rep. 2017. PMID: 29117556 Free PMC article.
Therapeutic targeting of transcriptional cyclin-dependent kinases.
Galbraith MD, Bender H, Espinosa JM. Galbraith MD, et al. Among authors: espinosa jm. Transcription. 2019 Apr;10(2):118-136. doi: 10.1080/21541264.2018.1539615. Epub 2018 Nov 9. Transcription. 2019. PMID: 30409083 Free PMC article. Review.
Transcriptional CDKs in the spotlight.
Espinosa JM. Espinosa JM. Transcription. 2019 Apr;10(2):45-46. doi: 10.1080/21541264.2019.1597479. Transcription. 2019. PMID: 30946639 Free PMC article. No abstract available.
174 results