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Lysosomal storage diseases: current therapies and future alternatives.
Leal AF, Espejo-Mojica AJ, Sánchez OF, Ramírez CM, Reyes LH, Cruz JC, Alméciga-Díaz CJ. Leal AF, et al. Among authors: espejo mojica aj. J Mol Med (Berl). 2020 Jul;98(7):931-946. doi: 10.1007/s00109-020-01935-6. Epub 2020 Jun 11. J Mol Med (Berl). 2020. PMID: 32529345 Review.
Human recombinant lysosomal β-Hexosaminidases produced in Pichia pastoris efficiently reduced lipid accumulation in Tay-Sachs fibroblasts.
Espejo-Mojica AJ, Rodríguez-López A, Li R, Zheng W, Alméciga-Díaz CJ, Dulcey-Sepúlveda C, Combariza G, Barrera LA. Espejo-Mojica AJ, et al. Am J Med Genet C Semin Med Genet. 2020 Dec;184(4):885-895. doi: 10.1002/ajmg.c.31849. Epub 2020 Oct 27. Am J Med Genet C Semin Med Genet. 2020. PMID: 33111489 Free PMC article.
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease.
Vu M, Li R, Baskfield A, Lu B, Farkhondeh A, Gorshkov K, Motabar O, Beers J, Chen G, Zou J, Espejo-Mojica AJ, Rodríguez-López A, Alméciga-Díaz CJ, Barrera LA, Jiang X, Ory DS, Marugan JJ, Zheng W. Vu M, et al. Orphanet J Rare Dis. 2018 Sep 17;13(1):152. doi: 10.1186/s13023-018-0886-3. Orphanet J Rare Dis. 2018. PMID: 30220252 Free PMC article.
Human recombinant lysosomal enzymes produced in microorganisms.
Espejo-Mojica ÁJ, Alméciga-Díaz CJ, Rodríguez A, Mosquera Á, Díaz D, Beltrán L, Díaz S, Pimentel N, Moreno J, Sánchez J, Sánchez OF, Córdoba H, Poutou-Piñales RA, Barrera LA. Espejo-Mojica ÁJ, et al. Mol Genet Metab. 2015 Sep-Oct;116(1-2):13-23. doi: 10.1016/j.ymgme.2015.06.001. Epub 2015 Jun 6. Mol Genet Metab. 2015. PMID: 26071627 Review.
20 results