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Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis.
Guyon J, Fernandez-Moncada I, Larrieu CM, Bouchez CL, Pagano Zottola AC, Galvis J, Chouleur T, Burban A, Joseph K, Ravi VM, Espedal H, Røsland GV, Daher B, Barre A, Dartigues B, Karkar S, Rudewicz J, Romero-Garmendia I, Klink B, Grützmann K, Derieppe MA, Molinié T, Obad N, Léon C, Seano G, Miletic H, Heiland DH, Marsicano G, Nikolski M, Bjerkvig R, Bikfalvi A, Daubon T. Guyon J, et al. Among authors: espedal h. EMBO Mol Med. 2022 Dec 7;14(12):e15343. doi: 10.15252/emmm.202115343. Epub 2022 Oct 24. EMBO Mol Med. 2022. PMID: 36278433 Free PMC article.
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.
Fack F, Espedal H, Keunen O, Golebiewska A, Obad N, Harter PN, Mittelbronn M, Bähr O, Weyerbrock A, Stuhr L, Miletic H, Sakariassen PØ, Stieber D, Rygh CB, Lund-Johansen M, Zheng L, Gottlieb E, Niclou SP, Bjerkvig R. Fack F, et al. Among authors: espedal h. Acta Neuropathol. 2015 Jan;129(1):115-31. doi: 10.1007/s00401-014-1352-5. Epub 2014 Oct 17. Acta Neuropathol. 2015. PMID: 25322816 Free PMC article.
Melanoma brain metastasis is independent of lactate dehydrogenase A expression.
Sundstrøm T, Espedal H, Harter PN, Fasmer KE, Skaftnesmo KO, Horn S, Hodneland E, Mittelbronn M, Weide B, Beschorner R, Bender B, Rygh CB, Lund-Johansen M, Bjerkvig R, Thorsen F. Sundstrøm T, et al. Among authors: espedal h. Neuro Oncol. 2015 Oct;17(10):1374-85. doi: 10.1093/neuonc/nov040. Epub 2015 Mar 19. Neuro Oncol. 2015. PMID: 25791837 Free PMC article.
Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival.
Gras Navarro A, Espedal H, Joseph JV, Trachsel-Moncho L, Bahador M, Gjertsen BT, Kristoffersen EK, Simonsen A, Miletic H, Enger PØ, Rahman MA, Chekenya M. Gras Navarro A, et al. Among authors: espedal h. Cancers (Basel). 2019 Jul 17;11(7):996. doi: 10.3390/cancers11070996. Cancers (Basel). 2019. PMID: 31319548 Free PMC article.
22 results