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Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood.
Burdorf L, Gao Z, Riner A, Sievert E, Harris DG, Kuravi KV, Morrill BH, Habibabady Z, Rybak E, Dahi S, Zhang T, Schwartz E, Kang E, Cheng X, Esmon CT, Phelps CJ, Ayares DL, Iii RNP, Azimzadeh AM. Burdorf L, et al. Among authors: esmon ct. Xenotransplantation. 2023 Nov-Dec;30(6):e12828. doi: 10.1111/xen.12828. Epub 2023 Sep 28. Xenotransplantation. 2023. PMID: 37767640
Blocking human protein C anticoagulant activity improves clotting defects of hemophilia mice expressing human protein C.
Jiang M, Yang F, Jiang Y, Cheng L, Han J, Yi J, Zhang G, Ma Z, Cao L, Zuo B, Zhou L, Huang L, Niu S, Xia Z, Zhou X, Bai X, Esmon NL, Ruan C, Xia L, Han Y, Esmon CT, Wu D, Xu J. Jiang M, et al. Among authors: esmon ct. Blood Adv. 2022 Jun 14;6(11):3304-3314. doi: 10.1182/bloodadvances.2021006214. Blood Adv. 2022. PMID: 35390147 Free PMC article.
Lipid presentation by the protein C receptor links coagulation with autoimmunity.
Müller-Calleja N, Hollerbach A, Royce J, Ritter S, Pedrosa D, Madhusudhan T, Teifel S, Meineck M, Häuser F, Canisius A, Nguyen TS, Braun J, Bruns K, Etzold A, Zechner U, Strand S, Radsak M, Strand D, Gu JM, Weinmann-Menke J, Esmon CT, Teyton L, Lackner KJ, Ruf W. Müller-Calleja N, et al. Among authors: esmon ct. Science. 2021 Mar 12;371(6534):eabc0956. doi: 10.1126/science.abc0956. Science. 2021. PMID: 33707237 Free PMC article.
388 results