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Value and limitation of in vitro bioassays to support the application of the threshold of toxicological concern to prioritise unidentified chemicals in food contact materials.
Schilter B, Burnett K, Eskes C, Geurts L, Jacquet M, Kirchnawy C, Oldring P, Pieper G, Pinter E, Tacker M, Traussnig H, Van Herwijnen P, Boobis A. Schilter B, et al. Among authors: eskes c. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 Dec;36(12):1903-1936. doi: 10.1080/19440049.2019.1664772. Epub 2019 Sep 24. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019. PMID: 31550212
Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks.
Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY, Ciccolallo L, Craig PS, De Vries RBM, Dorne JLCM, Druwe IL, Edwards SW, Eskes C, Georgiadis M, Hartung T, Kienzler A, Kristjansson EA, Lam J, Martino L, Meek B, Morgan RL, Munoz-Guajardo I, Noyes PD, Parmelli E, Piersma A, Rooney A, Sena E, Sullivan K, Tarazona J, Terron A, Thayer K, Turner J, Verbeek J, Verloo D, Vinken M, Watford S, Whaley P, Wikoff D, Willett K, Tsaioun K. Hoffmann S, et al. Among authors: eskes c. ALTEX. 2022;39(3):499–518. doi: 10.14573/altex.2202141. Epub 2022 Mar 1. ALTEX. 2022. PMID: 35258090 Free PMC article.
Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology - Evolution versus revolution.
Burgdorf T, Piersma AH, Landsiedel R, Clewell R, Kleinstreuer N, Oelgeschläger M, Desprez B, Kienhuis A, Bos P, de Vries R, de Wit L, Seidle T, Scheel J, Schönfelder G, van Benthem J, Vinggaard AM, Eskes C, Ezendam J. Burgdorf T, et al. Among authors: eskes c. Toxicol In Vitro. 2019 Sep;59:1-11. doi: 10.1016/j.tiv.2019.03.039. Epub 2019 Apr 1. Toxicol In Vitro. 2019. PMID: 30946968
Regulatory assessment of in vitro skin corrosion and irritation data within the European framework: Workshop recommendations.
Eskes C, Detappe V, Koëter H, Kreysa J, Liebsch M, Zuang V, Amcoff P, Barroso J, Cotovio J, Guest R, Hermann M, Hoffmann S, Masson P, Alépée N, Arce LA, Brüschweiler B, Catone T, Cihak R, Clouzeau J, D'Abrosca F, Delveaux C, Derouette JP, Engelking O, Facchini D, Fröhlicher M, Hofmann M, Hopf N, Molinari J, Oberli A, Ott M, Peter R, Sá-Rocha VM, Schenk D, Tomicic C, Vanparys P, Verdon B, Wallenhorst T, Winkler GC, Depallens O. Eskes C, et al. Regul Toxicol Pharmacol. 2012 Mar;62(2):393-403. doi: 10.1016/j.yrtph.2011.10.015. Epub 2011 Nov 6. Regul Toxicol Pharmacol. 2012. PMID: 22085589
International Harmonization and Cooperation in the Validation of Alternative Methods.
Barroso J, Ahn IY, Caldeira C, Carmichael PL, Casey W, Coecke S, Curren R, Desprez B, Eskes C, Griesinger C, Guo J, Hill E, Roi AJ, Kojima H, Li J, Lim CH, Moura W, Nishikawa A, Park H, Peng S, Presgrave O, Singer T, Sohn SJ, Westmoreland C, Whelan M, Yang X, Yang Y, Zuang V. Barroso J, et al. Among authors: eskes c. Adv Exp Med Biol. 2016;856:343-386. doi: 10.1007/978-3-319-33826-2_14. Adv Exp Med Biol. 2016. PMID: 27671730 Review.
One science-driven approach for the regulatory implementation of alternative methods: A multi-sector perspective.
Dal Negro G, Eskes C, Belz S, Bertein C, Chlebus M, Corvaro M, Corvi R, Dhalluin S, Halder M, Harvey J, Hermann M, Hoffmann-Dörr S, Kilian K, Lambrigts D, Laroche C, Louhimies S, Mahony C, Manou I, McNamee P, Prieto P, Reid K, Roggen E, Schutte K, Stirling C, Uhlrich S, Weissenhorn R, Whelan M. Dal Negro G, et al. Among authors: eskes c. Regul Toxicol Pharmacol. 2018 Nov;99:33-49. doi: 10.1016/j.yrtph.2018.08.002. Epub 2018 Aug 8. Regul Toxicol Pharmacol. 2018. PMID: 30098372 Free article.
Introduction.
Eskes C, Whelan M. Eskes C, et al. Adv Exp Med Biol. 2016;856:1-7. doi: 10.1007/978-3-319-33826-2_1. Adv Exp Med Biol. 2016. PMID: 27671717
Integrated Testing Strategies (ITS) for safety assessment.
Rovida C, Alépée N, Api AM, Basketter DA, Bois FY, Caloni F, Corsini E, Daneshian M, Eskes C, Ezendam J, Fuchs H, Hayden P, Hegele-Hartung C, Hoffmann S, Hubesch B, Jacobs MN, Jaworska J, Kleensang A, Kleinstreuer N, Lalko J, Landsiedel R, Lebreux F, Luechtefeld T, Locatelli M, Mehling A, Natsch A, Pitchford JW, Prater D, Prieto P, Schepky A, Schüürmann G, Smirnova L, Toole C, van Vliet E, Weisensee D, Hartung T. Rovida C, et al. Among authors: eskes c. ALTEX. 2015;32(1):25-40. doi: 10.14573/altex.1411011. Epub 2014 Nov 19. ALTEX. 2015. PMID: 25413849 Free article.
52 results