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Page 1
A comprehensive assessment of palmatine as anticonvulsant agent - In vivo and in silico studies.
Nieoczym D, Marszalek-Grabska M, Szalak R, Kundap U, Kaczor AA, Wrobel TM, Kosheva N, Komar M, Abram M, Esguerra CV, Samarut E, Pieróg M, Jakubiec M, Kaminski K, Kukula-Koch W, Gawel K. Nieoczym D, et al. Among authors: esguerra cv. Biomed Pharmacother. 2024 Mar;172:116234. doi: 10.1016/j.biopha.2024.116234. Epub 2024 Feb 6. Biomed Pharmacother. 2024. PMID: 38325264 Free article.
TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice.
Doboszewska U, Socała K, Pieróg M, Nieoczym D, Sawicki J, Szafarz M, Gawel K, Rafało-Ulińska A, Sajnóg A, Wyska E, Esguerra CV, Szewczyk B, Maćkowiak M, Barałkiewicz D, Mlyniec K, Nowak G, Sowa I, Wlaź P. Doboszewska U, et al. Among authors: esguerra cv. Cell Mol Life Sci. 2023 Apr 25;80(5):133. doi: 10.1007/s00018-023-04766-z. Cell Mol Life Sci. 2023. PMID: 37185787 Free PMC article.
Evaluation of the Antiseizure Activity of Endemic Plant Halfordia kendack Guillaumin and Its Main Constituent, Halfordin, on a Zebrafish Pentylenetetrazole (PTZ)-Induced Seizure Model.
Skiba A, Kozioł E, Luca SV, Budzyńska B, Podlasz P, Van Der Ent W, Shojaeinia E, Esguerra CV, Nour M, Marcourt L, Wolfender JL, Skalicka-Woźniak K. Skiba A, et al. Among authors: esguerra cv. Int J Mol Sci. 2023 Jan 30;24(3):2598. doi: 10.3390/ijms24032598. Int J Mol Sci. 2023. PMID: 36768918 Free PMC article.
Discovery of (R)-N-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [(R)-AS-1], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity In Vivo.
Abram M, Jakubiec M, Reeb K, Cheng MH, Gedschold R, Rapacz A, Mogilski S, Socała K, Nieoczym D, Szafarz M, Latacz G, Szulczyk B, Kalinowska-Tłuścik J, Gawel K, Esguerra CV, Wyska E, Müller CE, Bahar I, Fontana ACK, Wlaź P, Kamiński RM, Kamiński K. Abram M, et al. Among authors: esguerra cv. J Med Chem. 2022 Sep 8;65(17):11703-11725. doi: 10.1021/acs.jmedchem.2c00534. Epub 2022 Aug 19. J Med Chem. 2022. PMID: 35984707 Free PMC article.
SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility.
Silvennoinen K, Gawel K, Tsortouktzidis D, Pitsch J, Alhusaini S, van Loo KMJ, Picardo R, Michalak Z, Pagni S, Martins Custodio H, Mills J, Whelan CD, de Zubicaray GI, McMahon KL, van der Ent W, Kirstein-Smardzewska KJ, Tiraboschi E, Mudge JM, Frankish A, Thom M, Wright MJ, Thompson PM, Schoch S, Becker AJ, Esguerra CV, Sisodiya SM. Silvennoinen K, et al. Among authors: esguerra cv. Acta Neuropathol. 2022 Jul;144(1):107-127. doi: 10.1007/s00401-022-02429-0. Epub 2022 May 12. Acta Neuropathol. 2022. PMID: 35551471 Free PMC article.
53 results