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Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.
Griebel G, Pichat P, Beeské S, Leroy T, Redon N, Jacquet A, Françon D, Bert L, Even L, Lopez-Grancha M, Tolstykh T, Sun F, Yu Q, Brittain S, Arlt H, He T, Zhang B, Wiederschain D, Bertrand T, Houtmann J, Rak A, Vallée F, Michot N, Augé F, Menet V, Bergis OE, George P, Avenet P, Mikol V, Didier M, Escoubet J. Griebel G, et al. Among authors: escoubet j. Sci Rep. 2015 Jan 6;5:7642. doi: 10.1038/srep07642. Sci Rep. 2015. PMID: 25560837 Free PMC article.
ABHD11, a new diacylglycerol lipase involved in weight gain regulation.
Escoubet J, Kenigsberg M, Derock M, Yaligara V, Bock MD, Roche S, Massey F, de Foucauld H, Bettembourg C, Olivier A, Berthemy A, Capdevielle J, Legoux R, Perret E, Buzy A, Chardenot P, Destelle V, Leroy A, Cahours C, Teixeira S, Juvet P, Gauthier P, Leguet M, Rocheteau-Beaujouan L, Chatoux MA, Deshayes W, Clement M, Kabiri M, Orsini C, Mikol V, Didier M, Guillemot JC. Escoubet J, et al. PLoS One. 2020 Jun 24;15(6):e0234780. doi: 10.1371/journal.pone.0234780. eCollection 2020. PLoS One. 2020. PMID: 32579589 Free PMC article.