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Design, synthesis and antiviral evaluation of novel conjugates of the 1,7,7-trimethylbicyclo[2.2.1]heptane scaffold and saturated N-heterocycles via 1,2,3-triazole linker.
Sokolova AS, Yarovaya OI, Artyushin OI, Sharova EV, Baev DS, Mordvinova ED, Shcherbakov DN, Shnaider TA, Nikitina TV, Esaulkova IL, Ilyina PA, Zarubaev VV, Brel VK, Tolstikova TG, Salakhutdinov NF. Sokolova AS, et al. Among authors: esaulkova il. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300549. doi: 10.1002/ardp.202300549. Epub 2023 Nov 30. Arch Pharm (Weinheim). 2024. PMID: 38036303
Synthesis and Antiviral Activity of Camphene Derivatives against Different Types of Viruses.
Sokolova AS, Putilova VP, Yarovaya OI, Zybkina AV, Mordvinova ED, Zaykovskaya AV, Shcherbakov DN, Orshanskaya IR, Sinegubova EO, Esaulkova IL, Borisevich SS, Bormotov NI, Shishkina LN, Zarubaev VV, Pyankov OV, Maksyutov RA, Salakhutdinov NF. Sokolova AS, et al. Among authors: esaulkova il. Molecules. 2021 Apr 13;26(8):2235. doi: 10.3390/molecules26082235. Molecules. 2021. PMID: 33924393 Free PMC article.
Novel O-acylated amidoximes and substituted 1,2,4-oxadiazoles synthesised from (+)-ketopinic acid possessing potent virus-inhibiting activity against phylogenetically distinct influenza A viruses.
Chernyshov VV, Yarovaya OI, Esaulkova IL, Sinegubova E, Borisevich SS, Popadyuk II, Zarubaev VV, Salakhutdinov NF. Chernyshov VV, et al. Among authors: esaulkova il. Bioorg Med Chem Lett. 2022 Jan 1;55:128465. doi: 10.1016/j.bmcl.2021.128465. Epub 2021 Nov 19. Bioorg Med Chem Lett. 2022. PMID: 34808389
Novel 1,2,4-Triazole- and Tetrazole-Containing 4H-Thiopyrano[2,3-b]quinolines: Synthesis Based on the Thio-Michael/aza-Morita-Baylis-Hillman Tandem Reaction and Investigation of Antiviral Activity.
Khramchikhin AV, Skryl'nikova MA, Gureev MA, Zarubaev VV, Esaulkova IL, Ilyina PA, Mammeri OA, Spiridonova DV, Porozov YB, Ostrovskii VA. Khramchikhin AV, et al. Among authors: esaulkova il. Molecules. 2023 Nov 4;28(21):7427. doi: 10.3390/molecules28217427. Molecules. 2023. PMID: 37959845 Free PMC article.
Novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazine and [1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine Derivatives: Synthesis, Anti-Viral In Vitro Study and Target Validation Activity.
Khramchikhin AV, Skryl'nikova MA, Esaulkova IL, Sinegubova EO, Zarubaev VV, Gureev MA, Puzyk AM, Ostrovskii VA. Khramchikhin AV, et al. Among authors: esaulkova il. Molecules. 2022 Nov 16;27(22):7940. doi: 10.3390/molecules27227940. Molecules. 2022. PMID: 36432042 Free PMC article.
Synthesis and biological evaluation of 6-nitro-1,2,4-triazoloazines containing polyphenol fragments possessing antioxidant and antiviral activity.
Ulomskiy EN, Ivanova AV, Gorbunov EB, Esaulkova IL, Slita AV, Sinegubova EO, Voinkov EK, Drokin RA, Butorin II, Gazizullina ER, Gerasimova EL, Zarubaev VV, Rusinov VL. Ulomskiy EN, et al. Among authors: esaulkova il. Bioorg Med Chem Lett. 2020 Jul 1;30(13):127216. doi: 10.1016/j.bmcl.2020.127216. Epub 2020 Apr 27. Bioorg Med Chem Lett. 2020. PMID: 32360104
New heteroanalogs of tricyclic ascidian alkaloids: synthesis and biological activity.
Goryaeva MV, Kushch SO, Burgart YV, Ezhikova MA, Kodess MI, Slepukhin PA, Triandafilova GA, Krasnykh OP, Yakovleva EI, Zarubaev VV, Sinegubova EO, Esaulkova IL, Shtro AA, Galochkina AV, Nikolaeva YV, Saloutin VI. Goryaeva MV, et al. Among authors: esaulkova il. Org Biomol Chem. 2021 Nov 25;19(45):9925-9935. doi: 10.1039/d1ob01843d. Org Biomol Chem. 2021. PMID: 34735561