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Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.
Vaziri-Gohar A, Cassel J, Mohammed FS, Zarei M, Hue JJ, Hajihassani O, Graor HJ, Srikanth YVV, Karim SA, Abbas A, Prendergast E, Chen V, Katayama ES, Dukleska K, Khokhar I, Andren A, Zhang L, Wu C, Erokwu B, Flask CA, Zarei M, Wang R, Rothermel LD, Romani AMP, Bowers J, Getts R, Tatsuoka C, Morton JP, Bederman I, Brunengraber H, Lyssiotis CA, Salvino JM, Brody JR, Winter JM. Vaziri-Gohar A, et al. Among authors: erokwu b. Nat Cancer. 2022 Jul;3(7):852-865. doi: 10.1038/s43018-022-00393-y. Epub 2022 Jun 9. Nat Cancer. 2022. PMID: 35681100 Free PMC article.
Absence of leptin signaling allows fat accretion in cystic fibrosis mice.
Bederman IR, Pora G, O'Reilly M, Poleman J, Spoonhower K, Puchowicz M, Perez A, Erokwu BO, Rodriguez-Palacios A, Flask CA, Drumm ML. Bederman IR, et al. Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G685-G698. doi: 10.1152/ajpgi.00344.2017. Epub 2018 Aug 17. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 30118352 Free PMC article.
Ketones suppress brain glucose consumption.
LaManna JC, Salem N, Puchowicz M, Erokwu B, Koppaka S, Flask C, Lee Z. LaManna JC, et al. Among authors: erokwu b. Adv Exp Med Biol. 2009;645:301-6. doi: 10.1007/978-0-387-85998-9_45. Adv Exp Med Biol. 2009. PMID: 19227486 Free PMC article.
Targeted Radiosensitizers for MR-Guided Radiation Therapy of Prostate Cancer.
Luo D, Johnson A, Wang X, Li H, Erokwu BO, Springer S, Lou J, Ramamurthy G, Flask CA, Burda C, Meade TJ, Basilion JP. Luo D, et al. Among authors: erokwu bo. Nano Lett. 2020 Oct 14;20(10):7159-7167. doi: 10.1021/acs.nanolett.0c02487. Epub 2020 Aug 31. Nano Lett. 2020. PMID: 32845644 Free PMC article.
64 results