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The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue.
Pereira MJ, Palming J, Rizell M, Aureliano M, Carvalho E, Svensson MK, Eriksson JW. Pereira MJ, et al. Among authors: eriksson jw. Mol Cell Endocrinol. 2013 Jan 30;365(2):260-9. doi: 10.1016/j.mce.2012.10.030. Epub 2012 Nov 15. Mol Cell Endocrinol. 2013. PMID: 23160140
Differences between men and women in the regulation of adipose 11β-HSD1 and in its association with adiposity and insulin resistance.
DeSchoolmeester J, Palming J, Persson T, Pereira MJ, Wallerstedt E, Brown H, Gill D, Renström F, Lundgren M, Svensson MK, Rees A, Eriksson JW. DeSchoolmeester J, et al. Among authors: eriksson jw. Diabetes Obes Metab. 2013 Nov;15(11):1056-60. doi: 10.1111/dom.12137. Epub 2013 Jun 20. Diabetes Obes Metab. 2013. PMID: 23701286
Cyclosporine A and tacrolimus reduce the amount of GLUT4 at the cell surface in human adipocytes: increased endocytosis as a potential mechanism for the diabetogenic effects of immunosuppressive agents.
Pereira MJ, Palming J, Rizell M, Aureliano M, Carvalho E, Svensson MK, Eriksson JW. Pereira MJ, et al. Among authors: eriksson jw. J Clin Endocrinol Metab. 2014 Oct;99(10):E1885-94. doi: 10.1210/jc.2014-1266. Epub 2014 Jul 8. J Clin Endocrinol Metab. 2014. PMID: 25004245
232 results