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N'-substituted-2'-O,3'-N-carbonimidoyl bridged macrolides: novel anti-inflammatory macrolides without antimicrobial activity.
Bosnar M, Kragol G, Koštrun S, Vujasinović I, Bošnjak B, Bencetić Mihaljević V, Marušić Ištuk Z, Kapić S, Hrvačić B, Brajša K, Tavčar B, Jelić D, Glojnarić I, Verbanac D, Culić O, Padovan J, Alihodžić S, Eraković Haber V, Spaventi R. Bosnar M, et al. Among authors: erakovic haber v. J Med Chem. 2012 Jul 12;55(13):6111-23. doi: 10.1021/jm300356u. Epub 2012 Jun 25. J Med Chem. 2012. PMID: 22697905
The anti-inflammatory activity of clarithromycin inhibits TNFalpha production and prolongs survival following lipopolysaccharide administration in mice.
Tkalcević VI, Bosnjak B, Pasalić I, Hrvacić B, Situm K, Kramarić MD, Glojnarić I, Eraković Haber V. Tkalcević VI, et al. Among authors: erakovic haber v. Int J Antimicrob Agents. 2008 Aug;32(2):195-6. doi: 10.1016/j.ijantimicag.2008.03.016. Epub 2008 Jun 20. Int J Antimicrob Agents. 2008. PMID: 18571382 No abstract available.
Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte-macrophage colony-stimulating factor and interleukin-1beta.
Bosnar M, Bosnjak B, Cuzic S, Hrvacic B, Marjanovic N, Glojnaric I, Culic O, Parnham MJ, Erakovic Haber V. Bosnar M, et al. Among authors: erakovic haber v. J Pharmacol Exp Ther. 2009 Oct;331(1):104-13. doi: 10.1124/jpet.109.155838. Epub 2009 Jul 24. J Pharmacol Exp Ther. 2009. PMID: 19633061
Synthesis and biological activity of 4''-O-acyl derivatives of 14- and 15-membered macrolides linked to omega-quinolone-carboxylic unit.
Skugor MM, Stimac V, Palej I, Lugarić D, Paljetak HC, Filić D, Modrić M, Dilović I, Gembarovski D, Mutak S, Eraković Haber V, Holmes DJ, Ivezić-Schoenfeld Z, Alihodzić S. Skugor MM, et al. Among authors: erakovic haber v. Bioorg Med Chem. 2010 Sep 1;18(17):6547-58. doi: 10.1016/j.bmc.2010.06.050. Epub 2010 Jun 22. Bioorg Med Chem. 2010. PMID: 20621489
4''-O-(omega-Quinolylamino-alkylamino)propionyl derivatives of selected macrolides with the activity against the key erythromycin resistant respiratory pathogens.
Fajdetić A, Cipcić Paljetak H, Lazarevski G, Hutinec A, Alihodzić S, Derek M, Stimac V, Andreotti D, Sunjić V, Berge JM, Mutak S, Dumić M, Lociuro S, Holmes DJ, Marsić N, Eraković Haber V, Spaventi R. Fajdetić A, et al. Among authors: erakovic haber v. Bioorg Med Chem. 2010 Sep 1;18(17):6559-68. doi: 10.1016/j.bmc.2010.06.049. Epub 2010 Jun 22. Bioorg Med Chem. 2010. PMID: 20634078
42 results